Concepedia

Hormone Glucuronidation

Hormone Glucuronidation is a metabolic conjugation reaction in which glucuronic acid is covalently attached to a hormone via a glycosidic bond, primarily catalyzed by UDP-glucuronosyltransferase enzymes, to enhance its water solubility and facilitate biliary or renal excretion.

294

Publications

12.8K

Citations

918

Authors

284

Institutions

Publications per year

2017–2026

13

Parents

Publications

294

Analysis and occurrence of estrogenic hormones and their glucuronides in surface water and waste water in The Netherlands

A.C. Belfroid, Astrid van der Horst, A. Dick Vethaak et al. · The Science of The Total Environment · 1999 · 709 citations

, , +14

Relative Enzymatic Activity, Protein Stability, and Tissue Distribution of Human Steroid-Metabolizing UGT2B Subfamily Members**This work was supported by the Medical Research Council of Canada, the Fonds de la Recherche en Sante du Quebec, and Endorecherche.

David Turgeon, Jean-Sébastien Carrier, Éric Lévesque et al. · Endocrinology · 2001 · 330 citations

, , +16

Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans.

Chantal Guillemette, Robert C. Millikan, Beth Newman et al. · PubMed · 2000 · 206 citations

, , +13

Specificity and Regioselectivity of the Conjugation of Estradiol, Estrone, and Their Catecholestrogen and Methoxyestrogen Metabolites by Human Uridine Diphospho-glucuronosyltransferases Expressed in Endometrium

Johanie Lépine, Olivier Bernard, Marie Plante et al. · The Journal of Clinical Endocrinology & Metabolism · 2004 · 203 citations · Full text

, , +17

Characterization of Raloxifene Glucuronidation in Vitro: Contribution of Intestinal Metabolism to Presystemic Clearance

Daniel C. Kemp, Peter W. Fan, Jeffrey Stevens · Drug Metabolism and Disposition · 2002 · 192 citations

, , +14

1–5 of 294

Authors

918

  1. AB
    Alain Bélanger

    Université Laval, Canada

    23 publications · 1.4K citations

    18

    h-index

  2. DW
    Dean W. Hum

    Université Laval, Canada

    12 publications · 758 citations

    10

    h-index

  3. OB
    Olivier Barbier

    Université Laval, Canada

    13 publications · 440 citations

    10

    h-index

  4. WH
    William H. Fishman

    Tufts University, United States

    10 publications · 424 citations

    10

    h-index

  5. TR
    Thomas R. Tephly

    University of Iowa, United States

    8 publications · 449 citations

    8

    h-index

1–5 of 918

Institutions

284

  1. Université Laval

    Québec, Canada

    17 h-index

    92 publications

    5.8K citations

  2. University of Helsinki

    Helsinki, Finland

    11 h-index

    36 publications

    1K citations

  3. University of Iowa

    Iowa City, United States

    8 h-index

    20 publications

    1.2K citations

  4. University of Bonn

    Bonn, Germany

    7 h-index

    21 publications

    515 citations

  5. Erasmus MC

    Rotterdam, The Netherlands

    7 h-index

    27 publications

    1.8K citations

  6. Centre hospitalier de l'Université Laval

    Québec, Canada

    7 h-index

    27 publications

    1.4K citations

  7. Medical Council of Canada

    Ottawa, Canada

    7 h-index

    24 publications

    1.6K citations

  8. University of Dundee

    Dundee, United Kingdom

    7 h-index

    21 publications

    1.4K citations

1–8 of 284

Venues

  1. Drug Metabolism and Disposition

    22 publications · 1.3K citations

    18

    h-index

  2. Journal of Biological Chemistry

    JBC · 19 publications · 1.1K citations

    17

    h-index

  3. Endocrinology

    20 publications · 1.2K citations

    16

    h-index

  4. Steroids

    14 publications · 394 citations

    12

    h-index

  5. 12

    h-index

1–5