Peter W. Fan - Concepedia

Author

Peter W. Fan

Merck & Co., Inc., Rahway, NJ, USA (United States)

Also Known As

P W Fan, Peter W. Fan, Peter Fan, Peter W Fan, Peter W. Fan, Peter Wei-Jen Fan, Piaoran Fan

Publications

1.4K

Citations

H-Index

Concepts

All Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)Amgen (United States)University of Illinois Chicago Gilead Sciences (United States)Daiichi-Sankyo (Japan)

About

Peter W. Fan is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in pharmacology, medicine, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	14	16	633
2	Biochemistry	10	10	513
3	Natural Sciences	7	7	368
4	Engineering	2	2	77
5	Health Sciences	2	2	125

Peter W. Fan

Publications

1.3K

Citations

H-Index

Page 1

	Year	Citations
Characterization of Raloxifene Glucuronidation in Vitro: Contribution of Intestinal Metabolism to Presystemic Clearance Daniel C. Kemp, Peter W. Fan, Jeffrey Stevens Drug Metabolism and Disposition	2002	191
NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus Hans D. Brightbill, Eric Suto, Nicole Blaquière, Nature Communications	2018	120
4-Hydroxylated Metabolites of the Antiestrogens Tamoxifen and Toremifene Are Metabolized to Unusually Stable Quinone Methides Peter W. Fan, Fagen Zhang, Judy L. Bolton Chemical Research in Toxicology Chemoprevention StrategyQuinone Methide GshSecondary MetaboliteRedox BiologyOxidative Stress	1999	99
Characterization of Differential Tissue Abundance of Major Non-CYP Enzymes in Human Abdul Basit, Naveen K. Neradugomma, Christopher C. Wolford, Molecular Pharmaceutics PathologyRedox BiologyToxicological MechanismOxidative StressProtein Expression	2020	82
Synthesis and Reactivity of a Potential Carcinogenic Metabolite of Tamoxifen: 3,4-Dihydroxytamoxifen-<i>o</i>-quinone Fagen Zhang, Peter W. Fan, Xuemei Liu, Chemical Research in Toxicology Medicinal ChemistryPharmaceutical ChemistryBioorganic ChemistryAldehyde DehydrogenaseBiochemistry	1999	78
Bioactivation of tamoxifen to metabolite E quinone methide: reaction with glutathione and DNA. Peter W. Fan, Judy L. Bolton PubMed 4-Hydroxytamoxifen Quinone MethideSecondary MetaboliteRedox BiologyOxidative StressMedicinal Chemistry	2001	62
Diffusional Dissolution of Alumina in Various Steelmaking Slags Weol D. Cho, Peter W. Fan ISIJ International Materials ScienceMaterials EngineeringChemical EngineeringEngineeringPowder Metallurgy	2004	60
Linker Immolation Determines Cell Killing Activity of Disulfide-Linked Pyrrolobenzodiazepine Antibody–Drug Conjugates Donglu Zhang, Thomas H. Pillow, Yong Ma, ACS Medicinal Chemistry Letters	2016	54
Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-κB Inducing Kinase Nicole Blaquière, Georgette M. Castanedo, Jason D. Burch, Journal of Medicinal Chemistry Lead CompoundsDrug TargetLead IdentificationChemical BiologyPharmaceutical Chemistry	2018	51
4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase Emily J. Hanan, Matt Baumgardner, Marian C. Bryan, Bioorganic & Medicinal Chemistry Letters	2015	48

Page 1