Dean W. Hum

Elafibranor, an Agonist of the Peroxisome Proliferator−Activated Receptor−α and −δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening

Vlad Ratziu, Stephen A. Harrison, Sven Francque et al. · Gastroenterology · 2016 · 1K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +12

Hepatoprotective effects of the dual peroxisome proliferator-activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

Bart Staels, A. Rubenstrunk, Benoît Noël et al. · Hepatology · 2013 · 405 citations

Medicine, Pharmacology, Hepatology +15

Relative Enzymatic Activity, Protein Stability, and Tissue Distribution of Human Steroid-Metabolizing UGT2B Subfamily Members**This work was supported by the Medical Research Council of Canada, the Fonds de la Recherche en Sante du Quebec, and Endorecherche.

David Turgeon, Jean-Sébastien Carrier, Éric Lévesque et al. · Endocrinology · 2001 · 330 citations

Life Sciences, Biochemistry, Endocrinology +16

Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element

Thierry Claudel, Ekkehard Sturm, Hélène Duez et al. · Journal of Clinical Investigation · 2002 · 288 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element

Thierry Claudel, Ekkehard Sturm, Hélène Duez et al. · Journal of Clinical Investigation · 2002 · 276 citations

Life Sciences, Biochemistry, Molecular Biology +17