Genfit (France)

PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties

Mohamed Amine Bouhlel, Bruno Derudas, Elena Rigamonti et al. · Cell Metabolism · 2007 · 1.3K citations · Full text

Inflammation, Macrophage Biology, Cytokine +11

Elafibranor, an Agonist of the Peroxisome Proliferator−Activated Receptor−α and −δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening

Vlad Ratziu, Stephen A. Harrison, Sven Francque et al. · Gastroenterology · 2016 · 993 citations · Full text

Hepatoprotective effects of the dual peroxisome proliferator-activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

Bart Staels, A. Rubenstrunk, Benoît Noël et al. · Hepatology · 2013 · 402 citations

Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element

Thierry Claudel, Ekkehard Sturm, Hélène Duez et al. · Journal of Clinical Investigation · 2002 · 288 citations · Full text

Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element

Thierry Claudel, Ekkehard Sturm, Hélène Duez et al. · Journal of Clinical Investigation · 2002 · 273 citations · Full text

Promoter Activity, Molecular Biology, Fatty Liver Disease +19