Concepedia

High-throughput Activator Screening

High-Throughput Activator Screening is a systematic experimental method that enables the rapid and parallel evaluation of large compound libraries to identify molecules that enhance the activity of a target enzyme.

9

Publications

443

Citations

105

Authors

25

Institutions

Publications per year

2017–2026

4

Parents

Publications

9

Supramolecular Tandem Enzyme Assays

Roy N. Dsouza, Andreas Hennig, Werner M. Nau · Chemistry - A European Journal · 2012 · 143 citations

, , +17

Development of Neh2-Luciferase Reporter and Its Application for High Throughput Screening and Real-Time Monitoring of Nrf2 Activators

N. A. Smirnova, Renee Haskew-Layton, Manuela Basso et al. · Chemistry & Biology · 2011 · 100 citations

, , +11

Use of comprehensive screening methods to detect selective human CAR activators

Jenni Küblbeck, Tuomo Laitinen, Johanna Jyrkkärinne et al. · Biochemical Pharmacology · 2011 · 41 citations

, , +8

Microarrayed Compound Screening (μARCS) to Identify Activators and Inhibitors of AMP-Activated Protein Kinase

Steven N. Anderson, Barbara L. Cool, Lemma Kifle et al. · SLAS DISCOVERY · 2004 · 37 citations · Full text

, , +17

Discovery of<i>Tirasemtiv</i>, the First Direct Fast Skeletal Muscle Troponin Activator

Scott E. Collibee, Gustave Bergnes, Alexander R. Muci et al. · ACS Medicinal Chemistry Letters · 2018 · 30 citations · Full text

, , +8

1–5 of 9

Authors

105

  1. LK
    Lemma Kifle

    Abbott (United States), United States

    1 publications · 37 citations

    1

    h-index

  2. DJ
    David J. Burns

    Abbott Fund, United States

    1 publications · 37 citations

    1

    h-index

  3. FM
    Ferdinand Molnár

    University of Eastern Finland, Finland

    1 publications · 41 citations

    1

    h-index

  4. MS
    Madhavi S. Agrawal

    James Cook University, Australia

    1 publications · 25 citations

    1

    h-index

  5. NA
    N. A. Smirnova

    Cornell University, United States

    1 publications · 100 citations

    1

    h-index

1–5 of 105

Institutions

25

  1. Cytokinetics (United States)

    South San Francisco, United States

    1 h-index

    22 publications

    660 citations

  2. New York Medical College

    Valhalla, United States

    1 h-index

    1 publications

    100 citations

  3. The University of Texas at Austin

    Austin, United States

    1 h-index

    14 publications

    350 citations

  4. University of Pennsylvania

    Philadelphia, United States

    1 h-index

    2 publications

    48 citations

  5. Johns Hopkins University

    Baltimore, United States

    1 h-index

    2 publications

    200 citations

  6. Burke Medical Research Institute

    White Plains, United States

    1 h-index

    8 publications

    800 citations

  7. University of Eastern Finland

    Joensuu, Finland

    1 h-index

    7 publications

    287 citations

  8. Federal Institute For Materials Research and Testing

    Berlin, Germany

    1 h-index

    2 publications

    286 citations

1–8 of 25

Venues

  1. ACS Medicinal Chemistry Letters

    1 publications · 30 citations

    1

    h-index

  2. Bioorganic & Medicinal Chemistry Letters

    1 publications · 25 citations

    1

    h-index

  3. Chemistry & Biology

    1 publications · 100 citations

    1

    h-index

  4. SLAS DISCOVERY

    1 publications · 37 citations

    1

    h-index

  5. Cells Tissues Organs

    1 publications · 24 citations

    1

    h-index

1–5