Concepedia

Heritable Amplification

Heritable Amplification is a genetic phenomenon in which an oncogene undergoes duplication or multicopy increase in the genome and is stably transmitted across cell generations, thereby propagating enhanced oncogenic potential in a manner consistent with Mendelian or epigenetic inheritance patterns.

12

Publications

675

Citations

64

Authors

32

Institutions

Publications per year

2017–2026

1

Parents

Publications

12

Helicobacter pylori Infection Causes Characteristic DNA Damage Patterns in Human Cells

Max Koeppel, Fernando García-Alcalde, Frithjof Glowinski et al. · Cell Reports · 2015 · 141 citations · Full text

, , +17

Short Inverted-Repeat Transposable Elements in Teleost Fish and Implications for a Mechanism of Their Amplification

Zsuzsanna Izsvák, Zoltán Ivics, Nobuyoshi Shimoda et al. · Journal of Molecular Evolution · 1999 · 105 citations

, , +10

Suppression of Gene Amplification in Human Cell Hybrids

Thea D. Tlsty, Alicia White, Janet Sánchez · Science · 1992 · 75 citations

, , +15

The conserved helicase ZNFX-1 memorializes silenced RNAs in perinuclear condensates

John Paul T. Ouyang, Wenyan Lucy Zhang, Géraldine Seydoux · Nature Cell Biology · 2022 · 61 citations · Full text

, , +13

CELLULAR DIFFERENTIATION IN DICTYOSTELIACEAE: HERITABLE MODIFICATIONS OF THE DEVELOPMENTAL PATTERN

Raquel Sussman, Maurice Sussman · Annals of the New York Academy of Sciences · 1953 · 53 citations

, , +7

1–5 of 12

Authors

64

  1. PS
    Paul S. Meltzer

    National Institutes of Health, United States

    1 publications · 39 citations

    1

    h-index

  2. JP
    Joan P. Breyer

    Vanderbilt University, United States

    1 publications · 22 citations

    1

    h-index

  3. LA
    Laurence A. Rubin

    University of Toronto, Canada

    1 publications · 39 citations

    1

    h-index

  4. JA
    James A. Birchler

    University of Missouri, United States

    1 publications · 12 citations

    1

    h-index

  5. FG
    Fernando García-Alcalde

    Roche (Switzerland), Switzerland

    1 publications · 141 citations

    1

    h-index

1–5 of 64

Institutions

32

  1. University of Missouri

    Columbia, United States

    1 h-index

    2 publications

    24 citations

  2. Max Planck Institute for Evolutionary Biology

    Plön, Germany

    1 h-index

    1 publications

    32 citations

  3. Max Planck Society

    Munich, Germany

    1 h-index

    1 publications

    141 citations

  4. Johns Hopkins Medicine

    Baltimore, United States

    1 h-index

    3 publications

    183 citations

  5. Vanderbilt University

    Nashville, United States

    1 h-index

    2 publications

    44 citations

  6. American University of Beirut Medical Center

    Beirut, Lebanon

    1 h-index

    1 publications

    22 citations

  7. Massey University

    Palmerston North, New Zealand

    1 h-index

    1 publications

    32 citations

  8. Shanghai Cancer Institute

    Shanghai, China

    1 h-index

    1 publications

    22 citations

1–8 of 32

Venues

  1. Biochemistry

    1 publications · 33 citations

    1

    h-index

  2. Blood

    1 publications · 50 citations

    1

    h-index

  3. Genetics

    1 publications · 12 citations

    1

    h-index

  4. Cancer Epidemiology Biomarkers & Prevention

    CEBP · 1 publications · 22 citations

    1

    h-index

  5. Journal of Bone and Mineral Research

    JBMR · 1 publications · 39 citations

    1

    h-index

1–5