Concepedia

Hemoglobin Oxidation

Hemoglobin Oxidation is a biochemical process in which the iron atom within the heme group of hemoglobin undergoes a transition from the ferrous (Fe²⁺) to the ferric (Fe³⁺) state, resulting in the formation of methemoglobin and impairing oxygen binding and transport.

1.6K

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81.4K

Citations

4.5K

Authors

1.2K

Institutions

Publications per year

2017–2026

132

Parents

Publications

1.6K

Microsomal Heme Oxygenase

R Tenhunen, Harvey S. Marver, Rudi Schmid · Journal of Biological Chemistry · 1969 · 1.4K citations · Full text

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The Possible Significance of the Ferrous Oxidase Activity of Ceruloplasmin in Normal Human Serum

Shigemasa Osaki, Donald A. Johnson, Earl Frieden · Journal of Biological Chemistry · 1966 · 676 citations · Full text

, , +11

Iron promoters of the Fenton reaction and lipid peroxidation can be released from haemoglobin by peroxides

John M.C. Gutteridge · FEBS Letters · 1986 · 636 citations · Full text

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Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage.

József Balla, Harry S. Jacob, G Balla et al. · Proceedings of the National Academy of Sciences · 1993 · 594 citations · Full text

, , +17

Hemoglobin. A biologic fenton reagent.

S.M. Hossein Sadrzadeh, Ernst Graf, S. Scott Panter et al. · Journal of Biological Chemistry · 1984 · 589 citations · Full text

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Authors

4.5K

  1. AI
    Abdu I. Alayash

    Center for Biologics Evaluation and Research, United States

    46 publications · 2.5K citations

    30

    h-index

  2. PW
    Paul W. Buehler

    Center for Biologics Evaluation and Research, United States

    19 publications · 1.4K citations

    18

    h-index

  3. MT
    Michael T. Wilson

    University of Essex, United Kingdom

    15 publications · 1K citations

    14

    h-index

  4. MB
    Maurizio Brunori

    Sapienza University of Rome, Italy

    16 publications · 1.1K citations

    14

    h-index

  5. EA
    Eraldo Antonini

    Institute of Molecular Biology and Pathology, Italy

    15 publications · 751 citations

    14

    h-index

1–5 of 4.5K

Institutions

1.2K

  1. Center for Biologics Evaluation and Research

    Silver Spring, United States

    31 h-index

    137 publications

    8.2K citations

  2. National Institutes of Health

    Bethesda, United States

    25 h-index

    87 publications

    7.7K citations

  3. Albert Einstein College of Medicine

    Bronx, United States

    21 h-index

    87 publications

    5.4K citations

  4. Duke University

    Durham, United States

    19 h-index

    51 publications

    2.7K citations

  5. University of Essex

    Colchester, United Kingdom

    17 h-index

    83 publications

    5.5K citations

  6. University of Wisconsin–Madison

    Madison, United States

    17 h-index

    59 publications

    2.8K citations

  7. University of Pittsburgh

    Pittsburgh, United States

    16 h-index

    49 publications

    2K citations

  8. Harvard University

    Cambridge, United States

    15 h-index

    50 publications

    2K citations

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Venues

  1. Journal of Biological Chemistry

    JBC · 134 publications · 12.4K citations

    60

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  2. Biochemistry

    73 publications · 4.6K citations

    40

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  3. Free Radical Biology and Medicine

    34 publications · 1.7K citations

    26

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  4. Proceedings of the National Academy of Sciences

    PNAS · 26 publications · 3.8K citations

    25

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  5. PubMed

    Repository · 60 publications · 2.1K citations

    24

    h-index

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