Concepedia

Author

Abdu I. Alayash

Center for Biologics Evaluation and ResearchORCID

Also Known As

A Alayash, A I Alayash, A. Alayash, A. I. ALAYASH, A. I. Alayash, A.I. Al-Ayash, A.I. Alayash, ABDU I. ALAYASH, Abdu Alayash, Abdu I Alayash

189

Publications

8.4K

Citations

48

H-Index

101

Concepts

All Affiliations

Center for Biologics Evaluation and ResearchUnited States Food and Drug AdministrationNational Institutes of HealthUniversity of EssexDuke University
AI

About

Abdu I. Alayash is an author at Center for Biologics Evaluation and Research specializing in medicine, biochemistry, and redox biology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

30

51

2.2K

2

Biochemistry

29

47

1.9K

3

Health Sciences

16

18

797

4

Natural Sciences

16

16

693

5

Engineering

6

6

210

Abdu I. Alayash

×

102

Publications

5.3K

Citations

40

H-Index

YearCitations

Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

John D. Belcher, Chunsheng Chen, Julia Nguyen,

Blood

2013

671

CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin

Dominik J. Schaer, Christian A. Schaer, Paul W. Buehler,

Blood

2005

278

Sequestration of extracellular hemoglobin within a haptoglobin complex decreases its hypertensive and oxidative effects in dogs and guinea pigs

Felicitas S. Boretti, Paul W. Buehler, Felice D’Agnillo,

Journal of Clinical Investigation

2009

194

Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglobin from peroxidative modification

Paul W. Buehler, Bindu Abraham, Florence Vallelian,

Blood

2009

180

Structural Basis of Peroxide-mediated Changes in Human Hemoglobin

Yiping Jia, Paul W. Buehler, Robert A. Boykins,

Journal of Biological Chemistry

2006

148

Site-Specific Cross-Linking of Human and Bovine Hemoglobins Differentially Alters Oxygen Binding and Redox Side Reactions Producing Rhombic Heme and Heme Degradation

Enika Nagababu, Somasundaram Ramasamy, Joseph M. Rifkind,

Biochemistry

2002

113

Determination of extinction coefficients of human hemoglobin in various redox states

Fantao Meng, Abdu I. Alayash

Analytical Biochemistry

2017

113

Ascorbate removes key precursors to oxidative damage by cell-free haemoglobin <i>in vitro</i> and <i>in vivo</i>

Jacqueline Dunne, Alexis Caron, Patrick Menu,

Biochemical Journal

2006

100

Effects of Endogenous Ascorbate on Oxidation, Oxygenation, and Toxicokinetics of Cell-Free Modified Hemoglobin after Exchange Transfusion in Rat and Guinea Pig

Paul W. Buehler, Felice D’Agnillo, Victoria Hoffman,

Journal of Pharmacology and Experimental Therapeutics

2007

91

Peroxynitrite-Mediated Heme Oxidation and Protein Modification of Native and Chemically Modified Hemoglobins

Abdu I. Alayash, Beth A. Brockner Ryan, Robert E. Cashon

Archives of Biochemistry and Biophysics

1998

88

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