Concepedia

Gluconeogenesis

Gluconeogenesis is a metabolic pathway that serves as the primary mechanism for de novo glucose synthesis from non-carbohydrate precursors, distinguishing it from glycolysis and glycogenolysis by its anabolic function in maintaining blood glucose levels during fasting or stress.

3K

Publications

191.6K

Citations

12.1K

Authors

2.2K

Institutions

Publications per year

2017–2026

540

Parents

Publications

3K

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

Mark R. Owen, E. Doran, Andrew P. Halestrap · Biochemical Journal · 2000 · 2.1K citations · Full text

, , +17

The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin

Reuben J. Shaw, Katja Lamia, Debbie S. Vasquez et al. · Science · 2005 · 1.9K citations

, , +17

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

John C. Yoon, Pere Puigserver, Guoxun Chen et al. · Nature · 2001 · 1.8K citations

, , +14

Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction

Pere Puigserver, James Rhee, Jerry Donovan et al. · Nature · 2003 · 1.5K citations

, , +14

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

Stephan Herzig, Fanxin Long, Ulupi S. Jhala et al. · Nature · 2001 · 1.4K citations

, , +13

1–5 of 3K

Authors

12.1K

  1. VC
    Visvanathan Chandramouli

    Case Western Reserve University, United States

    30 publications · 3.9K citations

    25

    h-index

  2. BR
    Bernard R. Landau

    Case Western Reserve University, United States

    27 publications · 2.1K citations

    24

    h-index

  3. GI
    Gerald I. Shulman

    Yale University, United States

    27 publications · 8.2K citations

    24

    h-index

  4. AD
    Alan D. Cherrington

    Vanderbilt University, United States

    24 publications · 1.4K citations

    21

    h-index

  5. GM
    Gilles Mithieux

    Inserm, France

    22 publications · 3.9K citations

    20

    h-index

1–5 of 12.1K

Institutions

2.2K

  1. Harvard University

    Cambridge, United States

    49 h-index

    303 publications

    83.9K citations

  2. Vanderbilt University

    Nashville, United States

    45 h-index

    310 publications

    28.8K citations

  3. Inserm

    Paris, France

    36 h-index

    303 publications

    23.2K citations

  4. Case Western Reserve University

    Cleveland, United States

    36 h-index

    213 publications

    16.7K citations

  5. The University of Texas Southwestern Medical Center

    Dallas, United States

    35 h-index

    244 publications

    28.5K citations

  6. University of Pennsylvania

    Philadelphia, United States

    32 h-index

    160 publications

    15.5K citations

  7. Chinese Academy of Sciences

    Beijing, China

    30 h-index

    221 publications

    25.7K citations

  8. Yale University

    New Haven, United States

    30 h-index

    242 publications

    64.8K citations

1–8 of 2.2K

Venues

  1. Journal of Biological Chemistry

    JBC · 235 publications · 20.8K citations

    81

    h-index

  2. Diabetes

    165 publications · 16.4K citations

    71

    h-index

  3. 49

    h-index

  4. Journal of Clinical Investigation

    JCI · 47 publications · 9.5K citations

    42

    h-index

  5. Biochemical Journal

    BJ · 83 publications · 6.2K citations

    37

    h-index

1–5