Concepedia

Glucagon Analog Development

Glucagon Analog Development is a methodological contribution in metabolic pharmacology that involves the design and optimization of structurally modified glucagon derivatives to selectively modulate glucagon receptor signaling for therapeutic intervention in glucose homeostasis disorders.

15

Publications

441

Citations

74

Authors

18

Institutions

Publications per year

2017–2026

2

Parents

Publications

15

Optimization of the Native Glucagon Sequence for Medicinal Purposes

Joseph R. Chabenne, Maria A. DiMarchi, Vasily M. Gelfanov et al. · Journal of Diabetes Science and Technology · 2010 · 65 citations · Full text

, , +14

A glucagon analog chemically stabilized for immediate treatment of life-threatening hypoglycemia

Joseph R. Chabenne, Maria DiMarchi Chabenne, Yan Zhao et al. · Molecular Metabolism · 2014 · 60 citations · Full text

, , +14

Gcg-XTEN: An Improved Glucagon Capable of Preventing Hypoglycemia without Increasing Baseline Blood Glucose

Nathan C. Geething, Wayne To, Benjamin Spink et al. · PLoS ONE · 2010 · 59 citations · Full text

, , +16

Glucagon Antagonists: Contribution to Binding and Activity of the Amino-terminal Sequence 1–5, Position 12, and the Putative α-Helical Segment 19–27

Cecilia G. Unson, Ellen Gurzenda, K. Iwasa et al. · Journal of Biological Chemistry · 1989 · 40 citations · Full text

, , +17

Dasiglucagon, a next‐generation ready‐to‐use glucagon analog, for treatment of severe hypoglycemia in children and adolescents with type 1 diabetes: Results of a phase 3, randomized controlled trial

Tadej Battelino, Ramin Tehranchi, Timothy S. Bailey et al. · Pediatric Diabetes · 2021 · 35 citations · Full text

, , +14

1–5 of 15

Authors

74

  1. RD
    Richard D. DiMarchi

    Indiana University Bloomington, United States

    4 publications · 152 citations

    4

    h-index

  2. CG
    Cecilia G. Unson

    Rockefeller University, United States

    2 publications · 62 citations

    2

    h-index

  3. DL
    David L. Smiley

    Indiana University Bloomington, United States

    2 publications · 75 citations

    2

    h-index

  4. JR
    Joseph R. Chabenne

    Indiana University Bloomington, United States

    2 publications · 125 citations

    2

    h-index

  5. VM
    Vasily M. Gelfanov

    Indiana University Bloomington, United States

    2 publications · 125 citations

    2

    h-index

1–5 of 74

Institutions

18

  1. Indiana University Bloomington

    Bloomington, United States

    4 h-index

    18 publications

    779 citations

  2. Zealand Pharma (Denmark)

    Copenhagen, Denmark

    2 h-index

    4 publications

    124 citations

  3. Rockefeller University

    New York, United States

    2 h-index

    8 publications

    248 citations

  4. University of Copenhagen

    Copenhagen, Denmark

    1 h-index

    1 publications

    27 citations

  5. Ljubljana University Medical Centre

    Ljubljana, Slovenia

    1 h-index

    2 publications

    70 citations

  6. Amunix (United States)

    Mountain View, United States

    1 h-index

    10 publications

    590 citations

  7. Nankai University

    Tianjin, China

    1 h-index

    8 publications

    120 citations

  8. Kinderkrankenhaus auf der Bult

    Hanover, Germany

    1 h-index

    2 publications

    70 citations

1–8 of 18

Venues

  1. Journal of Biological Chemistry

    JBC · 2 publications · 62 citations

    2

    h-index

  2. Molecular and Cellular Endocrinology

    1 publications · 18 citations

    1

    h-index

  3. Life Sciences

    1 publications · 12 citations

    1

    h-index

  4. Tetrahedron Letters

    1 publications · 14 citations

    1

    h-index

  5. Diabetes Obesity and Metabolism

    1 publications · 27 citations

    1

    h-index

1–5