Concepedia

Germline Engineering

Germline Engineering is a genetic modification technique that alters the genome of germ cells or early embryonic cells, resulting in heritable changes that are transmitted to subsequent generations.

93

Publications

6.4K

Citations

466

Authors

214

Institutions

Publications per year

2017–2026

32

Variants

Germline Genetic Engineering

Parents

Publications

93

The Autosomal FLP-DFS Technique for Generating Germline Mosaics in <i>Drosophila melanogaster</i>

Tze-Bin Chou, Norbert Perrimon · Genetics · 1996 · 662 citations

, , +15

Don’t edit the human germ line

Edward H. Lanphier, Fyodor D. Urnov, Sarah Ehlen Haecker et al. · Nature · 2015 · 504 citations

, , +9

Germline transmission of genetically modified primordial germ cells

Marie‐Cecile van de Lavoir, Jennifer H. Diamond, Philip A. Leighton et al. · Nature · 2006 · 493 citations

, , +14

Induction of Atherosclerosis in Mice and Hamsters Without Germline Genetic Engineering

Martin M. Bjørklund, Anne Kruse Hollensen, Mette K. Hagensen et al. · Circulation Research · 2014 · 305 citations · Full text

, , +13

Germline integration of Moloney murine leukemia virus at the Mov13 locus leads to recessive lethal mutation and early embryonic death

Rudolf Jaenisch, Klaus Harbers, Angelika Schnieke et al. · Cell · 1983 · 258 citations

, , +17

1–5 of 93

Authors

466

  1. GM
    George M. Church

    Harvard University, United States

    4 publications · 254 citations

    4

    h-index

  2. TS
    Takashi Shinohara

    Kyoto University, Japan

    3 publications · 103 citations

    3

    h-index

  3. HZ
    Hong‐Ye Zhao

    Yunnan Agricultural University, China

    3 publications · 203 citations

    3

    h-index

  4. YG
    Yangbin Gao

    University of California San Diego, United States

    3 publications · 203 citations

    3

    h-index

  5. LY
    Luhan Yang

    Harvard University, United States

    3 publications · 203 citations

    3

    h-index

1–5 of 466

Institutions

214

  1. Harvard University

    Cambridge, United States

    8 h-index

    20 publications

    3.3K citations

  2. Stanford University

    Stanford, United States

    4 h-index

    6 publications

    781 citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    10 publications

    2.7K citations

  4. Kyoto University

    Kyoto, Japan

    3 h-index

    11 publications

    370 citations

  5. Yunnan Agricultural University

    Kunming, China

    3 h-index

    16 publications

    1.3K citations

  6. Baylor College of Medicine

    Houston, United States

    3 h-index

    14 publications

    1.5K citations

  7. University of Alabama at Birmingham

    Birmingham, United States

    2 h-index

    7 publications

    223 citations

  8. The University of Melbourne

    Melbourne, Australia

    2 h-index

    3 publications

    205 citations

1–8 of 214

Venues

  1. Biology of Reproduction

    6 publications · 274 citations

    6

    h-index

  2. PubMed

    Repository · 5 publications · 132 citations

    5

    h-index

  3. Nature

    5 publications · 1.1K citations

    5

    h-index

  4. 5

    h-index

  5. New England Journal of Medicine

    NEJM · 3 publications · 129 citations

    3

    h-index

1–5