Concepedia

Germander Hepatotoxicity

Germander Hepatotoxicity is a hepatotoxic response mediated by the ingestion of germander (Teucrium species), distinguished from other herb-induced liver injuries by its characteristic association with diterpenoid constituents that induce oxidative stress and cytotoxicity in hepatic tissues.

17

Publications

1.3K

Citations

78

Authors

26

Institutions

Publications per year

2017–2026

0

Parents

Publications

17

Hepatitis after Germander (<i>Teucrium chamaedrys</i>) Administration: Another Instance of Herbal Medicine Hepatotoxicity

Dominique Larrey, Thierry Vial, Arnaud Pauwels et al. · Annals of Internal Medicine · 1992 · 274 citations

, , +15

Hepatotoxicity of the Herbal Medicine Germander: Metabolic Activation of Its Furano Diterpenoids by Cytochrome P450 3A Depletes Cytoskeleton–Associated Protein Thiols and Forms Plasma Membrane Blebs in Rat Hepatocytes

Mounia Lekéhal, Dominique Pessayre, J M Lereau et al. · Hepatology · 1996 · 125 citations · Full text

, , +8

Diterpenoids from germander, an herbal medicine, induce apoptosis in isolated rat hepatocytes

Daniel Fau, Mounia Lekéhal, A. Moreau et al. · Gastroenterology · 1997 · 123 citations · Full text

, , +12

Hepatotoxicity of germander in mice

Jacqueline Loeper, Véronique Descatoire, Philippe Lettéron et al. · Gastroenterology · 1994 · 120 citations

, , +9

Hepatotoxicity of Germander (Teucrium chamaedrys L.) and One of Its Constituent Neoclerodane Diterpenes Teucrin A in the Mouse

Samir A. Kouzi, Randolph J. McMurtry, Sidney D. Nelson · Chemical Research in Toxicology · 1994 · 112 citations

, , +7

1–5 of 17

Authors

78

  1. DP
    Dominique Pessayre

    Inserm, France

    4 publications · 458 citations

    4

    h-index

  2. DF
    Daniel Fau

    Hôpital Beaujon, France

    3 publications · 368 citations

    3

    h-index

  3. ML
    Mounia Lekéhal

    Inserm, France

    2 publications · 248 citations

    2

    h-index

  4. AC
    A Castot

    Hôpital Fernand-Widal, France

    2 publications · 338 citations

    2

    h-index

  5. CM
    Claude Moulis

    Université Toulouse III - Paul Sabatier, France

    2 publications · 210 citations

    2

    h-index

1–5 of 78

Institutions

26

  1. Inserm

    Paris, France

    4 h-index

    25 publications

    2.8K citations

  2. Hôpital Beaujon

    Clichy, France

    4 h-index

    23 publications

    2.6K citations

  3. Université Paris Cité

    Paris, France

    1 h-index

    7 publications

    630 citations

  4. Hôpital Farhat Hached

    Sousse, Tunisia

    1 h-index

    1 publications

    44 citations

  5. Ospedale Santa Maria alle Scotte

    Siena, Italy

    1 h-index

    2 publications

    54 citations

  6. University of Washington

    Seattle, United States

    1 h-index

    3 publications

    336 citations

  7. Délégation Paris 5

    Paris, France

    1 h-index

    1 publications

    120 citations

  8. Université Toulouse III - Paul Sabatier

    Toulouse, France

    1 h-index

    7 publications

    630 citations

1–8 of 26

Venues

  1. PubMed

    Repository · 6 publications · 257 citations

    6

    h-index

  2. Gastroenterology

    2 publications · 243 citations

    2

    h-index

  3. 1

    h-index

  4. Phytochemical Analysis

    PCA · 1 publications · 38 citations

    1

    h-index

  5. Hepatology

    1 publications · 125 citations

    1

    h-index

1–5