Concepedia

Genetic Robustness

Genetic Robustness is a property of biological systems whereby the phenotype remains stable under genetic perturbations, particularly through epistatic interactions that buffer the effects of mutations.

166

Publications

16.6K

Citations

481

Authors

244

Institutions

Publications per year

2017–2026

24

Parents

Publications

166

Variation of the CGG repeat at the fragile X site results in genetic instability: Resolution of the Sherman paradox

Ying‐Hui Fu, Derek P.A. Kuhl, Antonio Pizzuti et al. · Cell · 1991 · 2.1K citations

, , +8

Genetic compensation induced by deleterious mutations but not gene knockdowns

Andrea Rossi, Zacharias Kontarakis, Claudia Gerri et al. · Nature · 2015 · 1.3K citations

, , +14

Role of duplicate genes in genetic robustness against null mutations

Zhenglong Gu, Lars M. Steinmetz, Xun Gu et al. · Nature · 2003 · 946 citations

, , +16

Principles for the Buffering of Genetic Variation

John L. Hartman, Barbara Garvik, Lee Hartwell · Science · 2001 · 706 citations

, , +14

Robustness and evolvability: a paradox resolved

Andreas Wagner · Proceedings of the Royal Society B Biological Sciences · 2007 · 688 citations

, , +17

1–5 of 166

Authors

481

  1. AW
    Andreas Wagner

    University of Zurich, Switzerland

    13 publications · 2.6K citations

    12

    h-index

  2. BC
    Bor‐Sen Chen

    National Tsing Hua University, Taiwan

    6 publications · 95 citations

    6

    h-index

  3. ML
    Mark L. Siegal

    New York University, United States

    5 publications · 605 citations

    5

    h-index

  4. SF
    Santiago F. Elena

    Instituto de Biología Molecular y Celular de Plantas, Spain

    5 publications · 565 citations

    5

    h-index

  5. KK
    Kunihiko Kaneko

    The University of Tokyo, Japan

    4 publications · 210 citations

    4

    h-index

1–5 of 481

Institutions

244

  1. Santa Fe Institute

    Santa Fe, United States

    14 h-index

    20 publications

    3.4K citations

  2. Yale University

    New Haven, United States

    9 h-index

    21 publications

    2.4K citations

  3. University of Zurich

    Zurich, Switzerland

    9 h-index

    14 publications

    1.4K citations

  4. Harvard University

    Cambridge, United States

    8 h-index

    25 publications

    4.2K citations

  5. SIB Swiss Institute of Bioinformatics

    Lausanne, Switzerland

    7 h-index

    11 publications

    1.5K citations

  6. Stanford University

    Stanford, United States

    7 h-index

    11 publications

    3.2K citations

  7. New York University

    New York, United States

    7 h-index

    13 publications

    1.4K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    21 publications

    1.4K citations

1–8 of 244

Venues

  1. PLoS ONE

    8 publications · 428 citations

    8

    h-index

  2. PLoS Computational Biology

    7 publications · 231 citations

    7

    h-index

  3. Evolution

    7 publications · 496 citations

    7

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 722 citations

    6

    h-index

  5. Journal of Theoretical Biology

    6 publications · 399 citations

    6

    h-index

1–5