Concepedia

Gene-based Association Testing

Gene-Based Association Testing is a statistical method in genome-wide association studies that aggregates genetic variants within a gene region to test for collective associations with a phenotype, distinguishing it from single-variant approaches by evaluating the joint effect of multiple variants within a biologically defined gene unit.

183

Publications

12.5K

Citations

1.8K

Authors

700

Institutions

Publications per year

2017–2026

86

Variants

Gene-based Association Analysis

Parents

Publications

183

A global test for groups of genes: testing association with a clinical outcome

Jelle J. Goeman, Sara A. van de Geer, Floor de Kort et al. · Bioinformatics · 2003 · 1.1K citations · Full text

, , +15

A Versatile Gene-Based Test for Genome-wide Association Studies

Jimmy Z. Liu, Allan F. McRae, Dale R. Nyholt et al. · The American Journal of Human Genetics · 2010 · 837 citations · Full text

, , +13

The Future of Association Studies: Gene-Based Analysis and Replication

Benjamin M. Neale, Pak C. Sham · The American Journal of Human Genetics · 2004 · 628 citations · Full text

, , +14

Flexible statistical methods for estimating and testing effects in genomic studies with multiple conditions

Sarah Urbut, Gao Wang, Peter Carbonetto et al. · Nature Genetics · 2018 · 480 citations

, , +8

Why, When and How to Adjust Your P Values?

Mohieddin Jafari, Naser Ansari‐Pour · PubMed · 2019 · 472 citations · Full text

, , +17

1–5 of 183

Authors

1.8K

  1. MJ
    Mark J. Daly

    Broad Institute, United States

    6 publications · 684 citations

    6

    h-index

  2. PC
    Pak C. Sham

    University of Hong Kong, Hong Kong SAR China

    5 publications · 1.1K citations

    5

    h-index

  3. BM
    Benjamin M. Neale

    Broad Institute, United States

    5 publications · 1.3K citations

    5

    h-index

  4. GR
    Gonçalo R. Abecasis

    University of Michigan, United States

    5 publications · 366 citations

    5

    h-index

  5. MB
    Michael Boehnke

    University of Michigan, United States

    5 publications · 237 citations

    5

    h-index

1–5 of 1.8K

Institutions

700

  1. Harvard University

    Cambridge, United States

    17 h-index

    22 publications

    1.2K citations

  2. Massachusetts General Hospital

    Boston, United States

    15 h-index

    18 publications

    1.3K citations

  3. Johns Hopkins University

    Baltimore, United States

    14 h-index

    16 publications

    669 citations

  4. University of Michigan

    Ann Arbor, United States

    13 h-index

    14 publications

    894 citations

  5. Broad Institute

    Cambridge, United States

    13 h-index

    16 publications

    1.2K citations

  6. Boston University

    Boston, United States

    11 h-index

    11 publications

    603 citations

  7. University of Washington

    Seattle, United States

    11 h-index

    13 publications

    558 citations

  8. National Institutes of Health

    Bethesda, United States

    11 h-index

    12 publications

    395 citations

1–8 of 700

Venues

  1. PLoS ONE

    15 publications · 491 citations

    12

    h-index

  2. The American Journal of Human Genetics

    AJHG · 12 publications · 2.5K citations

    11

    h-index

  3. Bioinformatics

    13 publications · 1.7K citations

    11

    h-index

  4. Genetic Epidemiology

    11 publications · 695 citations

    11

    h-index

  5. PLoS Genetics

    9 publications · 718 citations

    9

    h-index

1–5