Concepedia

Gene-based Association Analysis

Gene-Based Association Analysis is a statistical method in rare variant association studies that aggregates the effects of multiple variants within a gene to test for association with a phenotype, distinguishing it from variant-level or region-based approaches by focusing on the gene as the fundamental unit of analysis.

315

Publications

18.2K

Citations

3.7K

Authors

1.2K

Institutions

Publications per year

2017–2026

161

Variants

Gene-based Association Testing

Parents

Publications

315

A gene-based association method for mapping traits using reference transcriptome data

Eric R. Gamazon, Kaanan P. Shah, Sahar V. Mozaffari et al. · Nature Genetics · 2015 · 2.1K citations · Full text

, , +14

A global test for groups of genes: testing association with a clinical outcome

Jelle J. Goeman, Sara A. van de Geer, Floor de Kort et al. · Bioinformatics · 2003 · 1.1K citations · Full text

, , +15

A Versatile Gene-Based Test for Genome-wide Association Studies

Jimmy Z. Liu, Allan F. McRae, Dale R. Nyholt et al. · The American Journal of Human Genetics · 2010 · 837 citations · Full text

, , +13

The Future of Association Studies: Gene-Based Analysis and Replication

Benjamin M. Neale, Pak C. Sham · The American Journal of Human Genetics · 2004 · 628 citations · Full text

, , +14

Why, When and How to Adjust Your P Values?

Mohieddin Jafari, Naser Ansari‐Pour · PubMed · 2019 · 472 citations · Full text

, , +17

1–5 of 315

Authors

3.7K

  1. PC
    Pak C. Sham

    University of Hong Kong, Hong Kong SAR China

    7 publications · 933 citations

    7

    h-index

  2. NG
    Nicholas G. Martin

    QIMR Berghofer Medical Research Institute, Australia

    6 publications · 1.1K citations

    6

    h-index

  3. MB
    Michael Boehnke

    University of Michigan, United States

    6 publications · 360 citations

    6

    h-index

  4. EB
    Eric Boerwinkle

    The University of Texas Health Science Center at Houston, United States

    6 publications · 194 citations

    6

    h-index

  5. DL
    Dan L. Nicolae

    University of Chicago, United States

    5 publications · 2.7K citations

    5

    h-index

1–5 of 3.7K

Institutions

1.2K

  1. Harvard University

    Cambridge, United States

    21 h-index

    29 publications

    1.8K citations

  2. Johns Hopkins University

    Baltimore, United States

    17 h-index

    28 publications

    1.4K citations

  3. University of Michigan

    Ann Arbor, United States

    16 h-index

    17 publications

    1.2K citations

  4. Boston University

    Boston, United States

    15 h-index

    18 publications

    960 citations

  5. King's College London

    London, United Kingdom

    14 h-index

    19 publications

    1.4K citations

  6. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    14 h-index

    17 publications

    821 citations

  7. Broad Institute

    Cambridge, United States

    13 h-index

    15 publications

    1.1K citations

  8. Massachusetts General Hospital

    Boston, United States

    12 h-index

    13 publications

    877 citations

1–8 of 1.2K

Venues

  1. PLoS ONE

    36 publications · 1.2K citations

    22

    h-index

  2. Scientific Reports

    15 publications · 684 citations

    13

    h-index

  3. Frontiers in Genetics

    13 publications · 400 citations

    11

    h-index

  4. Bioinformatics

    10 publications · 1.5K citations

    10

    h-index

  5. PLoS Genetics

    9 publications · 808 citations

    9

    h-index

1–5