Concepedia

Gene Interaction Matrices

Gene Interaction Matrices is a computational framework that represents pairwise genetic interactions within a biological system by quantifying phenotypic deviations from expected combinatorial effects, organized in a matrix format where rows and columns correspond to genetic perturbations and matrix elements encode interaction strengths.

62

Publications

4.1K

Citations

261

Authors

136

Institutions

Publications per year

2017–2026

20

Parents

Publications

62

HiCRep: assessing the reproducibility of Hi-C data using a stratum-adjusted correlation coefficient

Tao Yang, Feipeng Zhang, Galip Gürkan Yardımcı et al. · Genome Research · 2017 · 617 citations · Full text

, , +15

High-throughput, quantitative analyses of genetic interactions in E. coli

Athanasios Typas, Robert J. Nichols, Deborah A. Siegele et al. · Nature Methods · 2008 · 246 citations · Full text

, , +15

HiCPlotter integrates genomic data with interaction matrices

Kadir C. Akdemir, Lynda Chin · Genome biology · 2015 · 241 citations · Full text

, , +16

Modeling Genetic Architecture: A Multilinear Theory of Gene Interaction

Thomas Fritz Hansen, Günter P. Wagner · Theoretical Population Biology · 2001 · 232 citations

, , +15

Enhancing Hi-C data resolution with deep convolutional neural network HiCPlus

Yan Zhang, Lin An, Jie Xu et al. · Nature Communications · 2018 · 204 citations · Full text

, , +16

1–5 of 62

Authors

261

  1. FY
    Feng Yue

    Pennsylvania State University, United States

    3 publications · 884 citations

    3

    h-index

  2. RC
    Ross C. Hardison

    Pennsylvania State University, United States

    2 publications · 680 citations

    2

    h-index

  3. GG
    Galip Gürkan Yardımcı

    University of Washington, United States

    2 publications · 680 citations

    2

    h-index

  4. QL
    Qunhua Li

    Pennsylvania State University, United States

    2 publications · 680 citations

    2

    h-index

  5. EZ
    Emile Zuckerkandl

    Palo Alto Institute, United States

    2 publications · 27 citations

    2

    h-index

1–5 of 261

Institutions

136

  1. Harvard University

    Cambridge, United States

    4 h-index

    8 publications

    397 citations

  2. Pennsylvania State University

    State College, United States

    3 h-index

    16 publications

    4.9K citations

  3. University of Pennsylvania

    Philadelphia, United States

    2 h-index

    5 publications

    92 citations

  4. University of Washington

    Seattle, United States

    2 h-index

    4 publications

    1.4K citations

  5. Institute for Systems Biology

    Seattle, United States

    2 h-index

    9 publications

    1.1K citations

  6. QB3

    San Francisco, United States

    2 h-index

    7 publications

    1.5K citations

  7. Harvard University Press

    Cambridge, United States

    2 h-index

    5 publications

    207 citations

  8. National Institutes of Health

    Bethesda, United States

    2 h-index

    9 publications

    387 citations

1–8 of 136

Venues

  1. Genome biology

    3 publications · 389 citations

    3

    h-index

  2. Nature Communications

    3 publications · 475 citations

    3

    h-index

  3. Journal of Molecular Evolution

    3 publications · 68 citations

    3

    h-index

  4. Hereditas

    2 publications · 23 citations

    2

    h-index

  5. Scientific Reports

    2 publications · 36 citations

    2

    h-index

1–5