Concepedia

Gene Dispensability

Gene Dispensability is a theoretical construct in evolutionary genomics that denotes the extent to which a gene can be lost from a genome without conferring a significant fitness cost to the organism under natural conditions.

21

Publications

2.4K

Citations

78

Authors

42

Institutions

Publications per year

2017–2026

2

Parents

Publications

21

Protein dispensability and rate of evolution

Aaron E. Hirsh, Hunter B. Fraser · Nature · 2001 · 425 citations

, , +5

Gene Loss, Protein Sequence Divergence, Gene Dispensability, Expression Level, and Interactivity Are Correlated in Eukaryotic Evolution

Dmitri M. Krylov, Yuri I. Wolf, Igor B. Rogozin et al. · Genome Research · 2003 · 410 citations · Full text

, , +16

Functional genomic analysis of the rates of protein evolution

Dennis P. Wall, Aaron E. Hirsh, Hunter B. Fraser et al. · Proceedings of the National Academy of Sciences · 2005 · 282 citations

, , +14

High-resolution yeast phenomics resolves different physiological features in the saline response

Jonas Warringer, Elke Ericson, Luciano Fernandez et al. · Proceedings of the National Academy of Sciences · 2003 · 245 citations · Full text

, , +17

Large-scale reduction of the <i>Bacillus subtilis</i> genome: consequences for the transcriptional network, resource allocation, and metabolism

Daniel R. Reuß, Josef Altenbuchner, Ulrike Mäder et al. · Genome Research · 2016 · 167 citations · Full text

, , +17

1–5 of 21

Authors

78

  1. AE
    Aaron E. Hirsh

    Stanford University, United States

    3 publications · 739 citations

    3

    h-index

  2. HB
    Hunter B. Fraser

    Stanford University, United States

    3 publications · 739 citations

    3

    h-index

  3. VS
    Vaughn S. Cooper

    University of Pittsburgh, United States

    2 publications · 65 citations

    2

    h-index

  4. YI
    Yuri I. Wolf

    National Center for Biotechnology Information, United States

    2 publications · 431 citations

    2

    h-index

  5. MB
    Michael B. Eisen

    University of California, Berkeley, United States

    1 publications · 282 citations

    1

    h-index

1–5 of 78

Institutions

42

  1. Stanford University

    Stanford, United States

    3 h-index

    9 publications

    2.4K citations

  2. University of California, Berkeley

    Berkeley, United States

    3 h-index

    11 publications

    2.1K citations

  3. University of New Hampshire

    Durham, United States

    2 h-index

    6 publications

    196 citations

  4. National Center for Biotechnology Information

    Bethesda, United States

    2 h-index

    5 publications

    1.7K citations

  5. University of Michigan

    Ann Arbor, United States

    2 h-index

    3 publications

    163 citations

  6. University of Chicago

    Chicago, United States

    2 h-index

    2 publications

    115 citations

  7. National Institutes of Health

    Bethesda, United States

    2 h-index

    5 publications

    1.7K citations

  8. Centre de Génétique Moléculaire

    Gif-sur-Yvette, France

    1 h-index

    1 publications

    125 citations

1–8 of 42

Venues

  1. Genome Research

    GR · 3 publications · 610 citations

    3

    h-index

  2. Genome Biology and Evolution

    GBE · 2 publications · 65 citations

    2

    h-index

  3. Molecular Biology and Evolution

    MBE · 2 publications · 212 citations

    2

    h-index

  4. Nature

    2 publications · 457 citations

    2

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 527 citations

    2

    h-index

1–5