High-resolution yeast phenomics resolves different physiological features in the saline response

Jonas Warringer, Elke Ericson, Luciano Fernandez, +2

Proceedings of the National Academy of Sciences

Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling

Fanny Langlet, Rebecca A. Haeusler, Daniel Lindén, +8

Cell

Selective InhibitionEnergy HomeostasisMedicineLiver PhysiologyPhysiology +7

Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action

Maureen E. Hillenmeyer, Elke Ericson, Ronald W. Davis, +3

Genome biology

Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast

Elke Ericson, Marinella Gebbia, Lawrence E. Heisler, +4

PLoS Genetics

Sensitivity ProfilesDrug TargetPsychopharmacologyMolecular BiologyPharmacotherapy +20

In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model

Alba Carreras, Luna Simona Pane, Roberto Nitsch, +17

BMC Biology

Therapeutic Genome Editing With CRISPR/Cas9 in a Humanized Mouse Model Ameliorates α1-antitrypsin Deficiency Phenotype

Mikael Bjursell, Michelle J. Porritt, Elke Ericson, +11

EBioMedicine

GeneticsImmunologyPathologyTherapeutic Genome EditingTranscriptional Regulation +16

Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death

Aleksandra A. Pandyra, Peter Mullen, Carolyn A. Goard, +13

Oncotarget

Chemical–Genetic Profiling of Imidazo[1,2-a]pyridines and -Pyrimidines Reveals Target Pathways Conserved between Yeast and Human Cells

Lisa Yu, Andrés López, Abderrahmane Anaflous, +10

PLoS Genetics

Fungal Cell BiologyMolecular BiologyMolecular GeneticsCompound 13Chemical Biology +15

A comprehensive platform for highly multiplexed mammalian functional genetic screens

Troy Ketela, Lawrence E. Heisler, Kevin R. Brown, +19

BMC Genomics

PROPHECY--a yeast phenome database, update 2006

Luciano Fernandez-Ricaud, Jonas Warringer, Elke Ericson, +6

Nucleic Acids Research

BiologyYeast Phenome DatabaseFunctional GenomicsEngineeringBiological Database +13