Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1

Ara Koh, Antonio Molinaro, Marcus Ståhlman, +15

Cell

Signal TransductionBiochemistryDiabetesMetabolic RegulationMetabolic Remodeling +4

Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in Mice

Valeriy Poroyko, Alba Carreras, Abdelnaby Khalyfa, +10

Scientific Reports

In vivo CRISPR editing with no detectable genome-wide off-target mutations

Pınar Akçakaya, Maggie Bobbin, Jimmy A. Guo, +19

Nature

Vivo CrisprNatural SciencesGeneticsMolecular BiologyGenetic Engineering +6

Fragmented Sleep Accelerates Tumor Growth and Progression through Recruitment of Tumor-Associated Macrophages and TLR4 Signaling

Fahed Hakim, Yang Wang, Shelley X. L. Zhang, +7

Cancer Research

Intermittent Hypoxia-induced Changes in Tumor-associated Macrophages and Tumor Malignancy in a Mouse Model of Sleep Apnea

Isaac Almendros, Yang Wang, Lev Becker, +9

American Journal of Respiratory and Critical Care Medicine

Chronic Sleep Fragmentation Induces Endothelial Dysfunction and Structural Vascular Changes in Mice

Alba Carreras, Shelley X. Zhang, Eduard Peris, +5

SLEEP

Disrupted sleep without sleep curtailment induces sleepiness and cognitive dysfunction via the tumor necrosis factor-α pathway

Vijay Ramesh, Deepti Nair, Shelley X. L. Zhang, +7

Journal of Neuroinflammation

Lipopolysaccharide-Binding Protein Plasma Levels in Children: Effects of Obstructive Sleep Apnea and Obesity

Eduard Peris, Yang Wang, Maximiliano Tamae Kakazu, +3

The Journal of Clinical Endocrinology & Metabolism

Sleep fragmentation promotes NADPH oxidase 2-mediated adipose tissue inflammation leading to insulin resistance in mice

Shelley X. L. Zhang, Abdelnaby Khalyfa, Yang Wang, +7

International Journal of Obesity

ObesityMetabolic SyndromeSleepInsulin SignalingBiochemistry +10

Chronic sleep fragmentation promotes obesity in young adult mice

Yang Wang, Alba Carreras, Seung‐Hoon Lee, +5

Obesity