Jimmy A. Guo

Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment

William L. Hwang, Karthik A. Jagadeesh, Jimmy A. Guo et al. · Nature Genetics · 2022 · 366 citations · Full text

Trajectory Analysis, Tumor Biology, Pancreatic Cancer +13

In vivo CRISPR editing with no detectable genome-wide off-target mutations

Pınar Akçakaya, Maggie Bobbin, Jimmy A. Guo et al. · Nature · 2018 · 315 citations · Full text

Vivo Crispr, Natural Sciences, Genetics +8

Activities and specificities of <scp>CRISPR</scp>/Cas9 and Cas12a nucleases for targeted mutagenesis in maize

Keunsub Lee, Yingxiao Zhang, Benjamin P. Kleinstiver et al. · Plant Biotechnology Journal · 2018 · 233 citations · Full text

Genetics, Molecular Biology, Maize Glossy2 Gene +16

Defining CRISPR–Cas9 genome-wide nuclease activities with CIRCLE-seq

Cícera R. Lazzarotto, Nathalie T. Nguyen, Xing Tang et al. · Nature Protocols · 2018 · 95 citations · Full text

Molecular Biology, Gene Editing, Genome Editing +2

Precise DNA cleavage using CRISPR-SpRYgests

Kathleen A. Christie, Jimmy A. Guo, Rachel A. Silverstein et al. · Nature Biotechnology · 2022 · 50 citations · Full text

Precise Dna Cleavage, Genetics, Molecular Biology +5