Concepedia

Gene Codon Optimization

Gene Codon Optimization is a computational molecular biology method that involves the systematic alteration of codon usage in a gene sequence to enhance its expression efficiency in a heterologous host system while preserving the encoded amino acid sequence.

378

Publications

21.6K

Citations

2.1K

Authors

652

Institutions

Publications per year

2017–2026

106

Parents

Publications

378

JCat: a novel tool to adapt codon usage of a target gene to its potential expression host

Andreas Grote, Karsten Hiller, Maurice Scheer et al. · Nucleic Acids Research · 2005 · 1.6K citations · Full text

, , +13

OPTIMIZER: a web server for optimizing the codon usage of DNA sequences

Pere Puigbò, Efrain Guzman, A. Romeu et al. · Nucleic Acids Research · 2007 · 620 citations · Full text

, , +13

Yeast-enhanced green fluorescent protein (yEGFP): a reporter of gene expression in Candida albicans

Brendan P. Cormack, Gwyneth Bertram, Mark Egerton et al. · Microbiology · 1997 · 602 citations

, , +17

Codon usage is an important determinant of gene expression levels largely through its effects on transcription

Zhipeng Zhou, Yunkun Dang, Mian Zhou et al. · Proceedings of the National Academy of Sciences · 2016 · 479 citations · Full text

, , +17

Gene Designer: a synthetic biology tool for constructing artificial DNA segments

Alan Villalobos, Jon E. Ness, Claes Gustafsson et al. · BMC Bioinformatics · 2006 · 377 citations · Full text

, , +15

1–5 of 378

Authors

2.1K

  1. RW
    Ralf Wagner

    University of Regensburg, Germany

    6 publications · 523 citations

    6

    h-index

  2. MG
    Marcus Graf

    University of Regensburg, Germany

    5 publications · 454 citations

    5

    h-index

  3. DL
    Dong‐Yup Lee

    Bioprocessing Technology Institute, Singapore

    5 publications · 314 citations

    5

    h-index

  4. AH
    Ali Hatef Salmanian

    National Institute of Genetic Engineering and Biotechnology, Iran

    4 publications · 86 citations

    4

    h-index

  5. WH
    Willem H. van Zyl

    Stellenbosch University, South Africa

    4 publications · 116 citations

    4

    h-index

1–5 of 2.1K

Institutions

652

  1. Chinese Academy of Sciences

    Beijing, China

    14 h-index

    84 publications

    6.3K citations

  2. Chinese Academy of Agricultural Sciences

    Beijing, China

    11 h-index

    78 publications

    2.8K citations

  3. Jiangnan University

    Wuxi, China

    8 h-index

    41 publications

    1.7K citations

  4. China Agricultural University

    Beijing, China

    8 h-index

    32 publications

    1K citations

  5. University College London

    London, United Kingdom

    7 h-index

    40 publications

    3.1K citations

  6. Seoul National University

    Seoul, South Korea

    6 h-index

    20 publications

    681 citations

  7. University of Oxford

    Oxford, United Kingdom

    6 h-index

    14 publications

    2.8K citations

  8. University of Regensburg

    Regensburg, Germany

    6 h-index

    21 publications

    2.3K citations

1–8 of 652

Venues

  1. Protein Expression and Purification

    20 publications · 1K citations

    18

    h-index

  2. Microbial Cell Factories

    16 publications · 793 citations

    15

    h-index

  3. PLoS ONE

    21 publications · 1.2K citations

    14

    h-index

  4. Journal of Virology

    JVI · 11 publications · 1.2K citations

    11

    h-index

  5. Applied Microbiology and Biotechnology

    11 publications · 372 citations

    11

    h-index

1–5