Concepedia

Fuzzy Protein Interactions

Fuzzy Protein Interactions is a theoretical construct in structural biology denoting protein–protein interactions characterized by dynamic and structurally heterogeneous binding interfaces that lack fixed, well-defined conformations, thereby enabling functional plasticity through variable interaction modes.

43

Publications

3.3K

Citations

221

Authors

120

Institutions

Publications per year

2017–2026

33

Variants

Fuzzy Protein Interaction

Parents

Publications

43

Fuzzy complexes: polymorphism and structural disorder in protein–protein interactions

Péter Tompa, Mónika Fuxreiter · Trends in Biochemical Sciences · 2007 · 1.1K citations

, , +16

The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy Complex

Peter S. Brzović, Clemens C. Heikaus, Leonid Kisselev et al. · Molecular Cell · 2011 · 224 citations · Full text

, , +15

Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex

Lisa M. Tuttle, Derek Pacheco, Linda Warfield et al. · Cell Reports · 2018 · 168 citations · Full text

, , +17

Sequence-Based Prediction of Fuzzy Protein Interactions

Márton Miskei, Attila Horváth, Michele Vendruscolo et al. · Journal of Molecular Biology · 2020 · 126 citations · Full text

, , +17

FuzDB: database of fuzzy complexes, a tool to develop stochastic structure-function relationships for protein complexes and higher-order assemblies

Márton Miskei, Csaba Antal, Mónika Fuxreiter · Nucleic Acids Research · 2016 · 117 citations · Full text

, , +17

1–5 of 43

Authors

221

  1. MF
    Mónika Fuxreiter

    University of Debrecen, Hungary

    7 publications · 1.5K citations

    7

    h-index

  2. DP
    Derek Pacheco

    Fred Hutch Cancer Center, United States

    5 publications · 595 citations

    5

    h-index

  3. SH
    Steven Hahn

    Fred Hutch Cancer Center, United States

    5 publications · 595 citations

    5

    h-index

  4. LW
    Linda Warfield

    Fred Hutch Cancer Center, United States

    5 publications · 595 citations

    5

    h-index

  5. RE
    Rachel E. Klevit

    University of Washington, United States

    4 publications · 569 citations

    4

    h-index

1–5 of 221

Institutions

120

  1. University of Debrecen

    Debrecen, Hungary

    6 h-index

    13 publications

    1.1K citations

  2. Fred Hutch Cancer Center

    Seattle, United States

    5 h-index

    23 publications

    2.9K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    22 publications

    1.3K citations

  4. University of Washington

    Seattle, United States

    5 h-index

    16 publications

    2.4K citations

  5. University of Ljubljana

    Ljubljana, Slovenia

    4 h-index

    11 publications

    281 citations

  6. Vrije Universiteit Brussel

    Brussels, Belgium

    4 h-index

    9 publications

    172 citations

  7. Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa

    Cape Town, South Africa

    3 h-index

    7 publications

    362 citations

  8. Inserm

    Paris, France

    3 h-index

    4 publications

    293 citations

1–8 of 120

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 222 citations

    3

    h-index

  2. Nucleic Acids Research

    3 publications · 219 citations

    3

    h-index

  3. Nature Communications

    3 publications · 105 citations

    3

    h-index

  4. Journal of Molecular Biology

    JMB · 3 publications · 207 citations

    3

    h-index

  5. Angewandte Chemie International Edition

    3 publications · 111 citations

    3

    h-index

1–5