Concepedia

Fungal Polyketide Synthases

Fungal Polyketide Synthases is a class of multidomain enzymatic systems in fungi that orchestrate the biosynthesis of polyketide secondary metabolites through iterative decarboxylative Claisen condensations of malonyl-CoA extender units, distinguished by their modular architecture and substrate specificity in generating structurally diverse bioactive compounds.

590

Publications

35.9K

Citations

2.4K

Authors

702

Institutions

Publications per year

2017–2026

171

Parents

Publications

590

Phylogenomic analysis of type I polyketide synthase genes in pathogenic and saprobic ascomycetes

Scott Kroken, N. Louise Glass, John W. Taylor et al. · Proceedings of the National Academy of Sciences · 2003 · 523 citations · Full text

, , +17

The <i>akuB</i> <sup>KU80</sup> Mutant Deficient for Nonhomologous End Joining Is a Powerful Tool for Analyzing Pathogenicity in <i>Aspergillus fumigatus</i>

Márcia Eliana da Silva Ferreira, Márcia Regina von Zeska Kress, Marcela Savoldi et al. · Eukaryotic Cell · 2006 · 401 citations · Full text

, , +15

Complete Reconstitution of a Highly Reducing Iterative Polyketide Synthase

Magali Suzanne, Jesse W.-H. Li, Jin Wook Choi et al. · Science · 2009 · 385 citations · Full text

, , +17

Secondary metabolism in Trichoderma – a genomic perspective

Prasun K. Mukherjee, Benjamin A. Horwitz, Charles M. Kenerley · Microbiology · 2011 · 355 citations · Full text

, , +17

A Gene Cluster Containing Two Fungal Polyketide Synthases Encodes the Biosynthetic Pathway for a Polyketide, Asperfuranone, in <i>Aspergillus nidulans</i>

Yi‐Ming Chiang, Edyta Szewczyk, Ashley D. Davidson et al. · Journal of the American Chemical Society · 2009 · 341 citations · Full text

, , +17

1–5 of 590

Authors

2.4K

  1. YT
    Yi Tang

    University of California, Los Angeles, United States

    35 publications · 2.9K citations

    29

    h-index

  2. IF
    Isao Fujii

    The University of Tokyo, Japan

    31 publications · 2K citations

    22

    h-index

  3. RJ
    Russell J. Cox

    University of Bristol, United Kingdom

    25 publications · 2K citations

    21

    h-index

  4. TJ
    Thomas J. Simpson

    University of Bristol, United Kingdom

    24 publications · 2K citations

    21

    h-index

  5. YE
    Yutaka Ebizuka

    The University of Tokyo, Japan

    23 publications · 1.6K citations

    18

    h-index

1–5 of 2.4K

Institutions

702

  1. University of California, Los Angeles

    Los Angeles, United States

    30 h-index

    155 publications

    13.6K citations

  2. The University of Tokyo

    Tokyo, Japan

    28 h-index

    134 publications

    8.3K citations

  3. University of Bristol

    Bristol, United Kingdom

    25 h-index

    146 publications

    12.9K citations

  4. Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)

    Jena, Germany

    23 h-index

    88 publications

    6.3K citations

  5. Chinese Academy of Sciences

    Beijing, China

    20 h-index

    123 publications

    6.2K citations

  6. Johns Hopkins University

    Baltimore, United States

    17 h-index

    53 publications

    3.6K citations

  7. Hokkaido University

    Sapporo, Japan

    17 h-index

    65 publications

    4.4K citations

  8. Friedrich Schiller University Jena

    Jena, Germany

    17 h-index

    45 publications

    3.7K citations

1–8 of 702

Venues

  1. Journal of the American Chemical Society

    JACS · 39 publications · 3.8K citations

    34

    h-index

  2. Organic Letters

    OL · 21 publications · 935 citations

    19

    h-index

  3. Applied and Environmental Microbiology

    AEM · 22 publications · 2.1K citations

    19

    h-index

  4. ChemBioChem

    22 publications · 1.4K citations

    18

    h-index

  5. Angewandte Chemie International Edition

    20 publications · 885 citations

    18

    h-index

1–5