Concepedia

Functional Genomics Screening

Functional Genomics Screening is a systematic experimental approach within molecular biology that employs CRISPR-based perturbations to identify and characterize the biological functions of genes by observing phenotypic outcomes across genome-wide or targeted genetic modifications.

205

Publications

23.9K

Citations

1.9K

Authors

411

Institutions

Publications per year

2017–2026

115

Parents

Publications

205

MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens

Wei Li, Han Xu, Tengfei Xiao et al. · Genome biology · 2014 · 2.8K citations · Full text

, , +17

Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities

Kendall R Sanson, Ruth E. Hanna, Mudra Hegde et al. · Nature Communications · 2018 · 1.1K citations · Full text

, , +16

Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference

Kumiko Ui‐Tei · Nucleic Acids Research · 2004 · 816 citations

, , +14

CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells

Siyuan Liu, Max A. Horlbeck, Seung Woo Cho et al. · Science · 2016 · 770 citations

, , +17

High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells

Yuexin Zhou, Shiyou Zhu, Changzu Cai et al. · Nature · 2014 · 762 citations

, , +17

1–5 of 205

Authors

1.9K

  1. DE
    David E. Root

    Broad Institute, United States

    7 publications · 1.3K citations

    7

    h-index

  2. MK
    Martin Kampmann

    University of California, San Francisco, United States

    7 publications · 1.3K citations

    7

    h-index

  3. TH
    Traver Hart

    The University of Texas MD Anderson Cancer Center, United States

    5 publications · 422 citations

    5

    h-index

  4. NE
    Neville E. Sanjana

    New York Genome Center, United States

    5 publications · 754 citations

    5

    h-index

  5. JG
    John G. Doench

    Broad Institute, United States

    5 publications · 1.4K citations

    5

    h-index

1–5 of 1.9K

Institutions

411

  1. Broad Institute

    Cambridge, United States

    24 h-index

    160 publications

    32.3K citations

  2. Harvard University

    Cambridge, United States

    22 h-index

    110 publications

    13.7K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    17 h-index

    46 publications

    7.2K citations

  4. University of California, San Francisco

    San Francisco, United States

    15 h-index

    88 publications

    20.9K citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    13 h-index

    39 publications

    5.1K citations

  6. Stanford University

    Stanford, United States

    12 h-index

    70 publications

    11.8K citations

  7. Dana-Farber Cancer Institute

    Boston, United States

    10 h-index

    53 publications

    25.3K citations

  8. Yale University

    New Haven, United States

    8 h-index

    35 publications

    2.3K citations

1–8 of 411

Venues

  1. Nature Communications

    12 publications · 1.9K citations

    12

    h-index

  2. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 11 publications · 225 citations

    10

    h-index

  3. Nucleic Acids Research

    10 publications · 1.2K citations

    10

    h-index

  4. Genome biology

    9 publications · 3.8K citations

    9

    h-index

  5. Scientific Reports

    6 publications · 369 citations

    6

    h-index

1–5