Concepedia

Functional Gene Reconstitution

Functional Gene Reconstitution is a therapeutic strategy in stem cell gene therapy that involves the precise integration of a corrected or exogenous gene into the genome of a stem cell to restore or establish a missing or impaired biological function.

54

Publications

4K

Citations

296

Authors

104

Institutions

Publications per year

2017–2026

6

Parents

Publications

54

Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR)

Christine E. Bear, Canhui Li, Norbert Kartner et al. · Cell · 1992 · 946 citations

, , +14

Construction of plasmids carrying the cI gene of bacteriophage lambda.

Keith Backman, Mark Ptashne, W Gilbert · Proceedings of the National Academy of Sciences · 1976 · 410 citations · Full text

, , +16

Identification and functional reconstitution of the yeast peroxisomal adenine nucleotide transporter

Luigi Palmieri, Hanspeter Rottensteiner, Wolfgang Girzalsky et al. · The EMBO Journal · 2001 · 200 citations · Full text

, , +8

Functional reconstitution of bacterial Tat translocation in vitro

Timothy L. Yahr · The EMBO Journal · 2001 · 169 citations · Full text

, , +5

The Sequence, Bacterial Expression, and Functional Reconstitution of the Rat Mitochondrial Dicarboxylate Transporter Cloned via Distant Homologs in Yeast and Caenorhabditis elegans

Giuseppe Fiermonte, Luigi Palmieri, Vincenza Dolce et al. · Journal of Biological Chemistry · 1998 · 134 citations · Full text

, , +13

1–5 of 54

Authors

296

  1. FP
    Ferdinando Palmieri

    University of Bari Aldo Moro, Italy

    2 publications · 334 citations

    2

    h-index

  2. JR
    James R. Stringer

    University of Cincinnati Medical Center, United States

    2 publications · 44 citations

    2

    h-index

  3. WH
    Wei-Shau Hu

    National Cancer Institute, United States

    2 publications · 84 citations

    2

    h-index

  4. CK
    Christine Kinnon

    University College London, United Kingdom

    2 publications · 32 citations

    2

    h-index

  5. JL
    Jane Lebkowski

    Menlo School, United States

    2 publications · 32 citations

    2

    h-index

1–5 of 296

Institutions

104

  1. University of Bari Aldo Moro

    Bari, Italy

    3 h-index

    12 publications

    1.4K citations

  2. Case Western Reserve University

    Cleveland, United States

    2 h-index

    13 publications

    666 citations

  3. University of Toronto

    Toronto, Canada

    2 h-index

    7 publications

    4.8K citations

  4. Johns Hopkins Medicine

    Baltimore, United States

    2 h-index

    18 publications

    1.3K citations

  5. Freie Universität Berlin

    Berlin, Germany

    2 h-index

    7 publications

    856 citations

  6. The University of Tokyo

    Tokyo, Japan

    2 h-index

    7 publications

    264 citations

  7. Johns Hopkins University

    Baltimore, United States

    2 h-index

    18 publications

    1.3K citations

  8. Humboldt-Universität zu Berlin

    Berlin, Germany

    2 h-index

    4 publications

    100 citations

1–8 of 104

Venues

  1. Journal of Biological Chemistry

    JBC · 5 publications · 444 citations

    5

    h-index

  2. Protein Expression and Purification

    4 publications · 113 citations

    4

    h-index

  3. Cell

    3 publications · 1.1K citations

    3

    h-index

  4. ACS Synthetic Biology

    2 publications · 107 citations

    2

    h-index

  5. The Journal of Immunology

    JI · 2 publications · 102 citations

    2

    h-index

1–5