Concepedia

Functional Enrichment Analysis

Functional Enrichment Analysis is a bioinformatics statistical method that, given a set of genes (typically derived from high-throughput gene expression experiments), tests for and quantifies the over- or under-representation of predefined functional categories (such as Gene Ontology terms or pathways) relative to an appropriate background set in order to infer underlying biological processes, functions, or mechanisms.

807

Publications

271.5K

Citations

3.8K

Authors

1.2K

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Publications per year

2017–2026

331

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Publications

807

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 56.7K citations · Full text

, , +12

GSVA: gene set variation analysis for microarray and RNA-Seq data

Sonja Hänzelmann, Robert Castelo, Justin Guinney · BMC Bioinformatics · 2013 · 16.5K citations · Full text

, , +17

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

Da Wei Huang, Brad T. Sherman, Richard A. Lempicki · Nucleic Acids Research · 2008 · 14.7K citations · Full text

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clusterProfiler 4.0: A universal enrichment tool for interpreting omics data

Tianzhi Wu, Erqiang Hu, Shuangbin Xu et al. · The Innovation · 2021 · 12.7K citations · Full text

, , +13

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

Maxim V. Kuleshov, Matthew R. Jones, Andrew D. Rouillard et al. · Nucleic Acids Research · 2016 · 11.7K citations · Full text

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1–5 of 807

Authors

3.8K

  1. AM
    Avi Ma’ayan

    Icahn School of Medicine at Mount Sinai, United States

    13 publications · 23.4K citations

    13

    h-index

  2. JD
    Joaquı́n Dopazo

    Centro de Investigacion Principe Felipe, Spain

    11 publications · 1.9K citations

    10

    h-index

  3. MA
    Maureen A. Sartor

    University of Michigan, United States

    8 publications · 515 citations

    8

    h-index

  4. FA
    Fátima Al‐Shahrour

    Spanish National Cancer Research Centre, Spain

    7 publications · 1.7K citations

    7

    h-index

  5. NH
    Nigam H. Shah

    Stanford University, United States

    7 publications · 396 citations

    7

    h-index

1–5 of 3.8K

Institutions

1.2K

  1. Harvard University

    Cambridge, United States

    20 h-index

    119 publications

    33.8K citations

  2. University of Michigan

    Ann Arbor, United States

    17 h-index

    73 publications

    8.3K citations

  3. Icahn School of Medicine at Mount Sinai

    New York, United States

    17 h-index

    98 publications

    236K citations

  4. Stanford University

    Stanford, United States

    17 h-index

    68 publications

    20K citations

  5. SIB Swiss Institute of Bioinformatics

    Lausanne, Switzerland

    12 h-index

    38 publications

    4K citations

  6. Harbin Medical University

    Harbin, China

    12 h-index

    106 publications

    5.7K citations

  7. Chinese Academy of Sciences

    Beijing, China

    12 h-index

    33 publications

    19.2K citations

  8. University of Cambridge

    Cambridge, United Kingdom

    11 h-index

    19 publications

    2.5K citations

1–8 of 1.2K

Venues

  1. Nucleic Acids Research

    84 publications · 65.8K citations

    60

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  2. Bioinformatics

    108 publications · 35.8K citations

    52

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  3. BMC Bioinformatics

    96 publications · 37.2K citations

    40

    h-index

  4. PLoS ONE

    41 publications · 11.3K citations

    26

    h-index

  5. BMC Genomics

    31 publications · 1.4K citations

    19

    h-index

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