Concepedia

Focal Adhesion Assembly

Focal Adhesion Assembly is a cellular process that involves the organized recruitment and integration of structural and signaling proteins at sites of integrin-mediated cell-extracellular matrix contact, thereby establishing stable anchoring complexes that facilitate mechanotransduction, cytoskeletal regulation, and downstream signaling events.

585

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3K

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812

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2017–2026

93

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Publications

585

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

Anne J. Ridley, Alan Hall · Cell · 1992 · 4.5K citations

, , +17

Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates

Nathalie Q. Balaban, Ulrich S. Schwarz, Daniel Riveline et al. · Nature Cell Biology · 2001 · 2.1K citations

, , +14

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

Duško llić, Yasuhide Furuta, S. Kanazawa et al. · Nature · 1995 · 1.8K citations

, , +16

Focal Contacts as Mechanosensors

Daniel Riveline, Eli Zamir, Nathalie Q. Balaban et al. · The Journal of Cell Biology · 2001 · 1.4K citations · Full text

, , +17

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.

Keith Burridge, Christopher E. Turner, Lewis H. Romer · The Journal of Cell Biology · 1992 · 1.3K citations · Full text

, , +17

1–5 of 585

Authors

3K

  1. DR
    David R. Critchley

    University of Leicester, United Kingdom

    14 publications · 2.1K citations

    14

    h-index

  2. BG
    Benjamin Geiger

    Weizmann Institute of Science, Israel

    13 publications · 5.6K citations

    13

    h-index

  3. JC
    John Couchman

    University of Alabama at Birmingham, United States

    9 publications · 968 citations

    9

    h-index

  4. CW
    Chuanyue Wu

    University of Pittsburgh, United States

    8 publications · 734 citations

    8

    h-index

  5. AJ
    Andrés J. Garcı́a

    Georgia Institute of Technology, United States

    8 publications · 1.6K citations

    8

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1–5 of 3K

Institutions

812

  1. Centre National de la Recherche Scientifique

    Paris, France

    19 h-index

    78 publications

    6.7K citations

  2. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    17 h-index

    53 publications

    8.6K citations

  3. Harvard University

    Cambridge, United States

    17 h-index

    62 publications

    8.8K citations

  4. Weizmann Institute of Science

    Rehovot, Israel

    15 h-index

    62 publications

    40.7K citations

  5. Inserm

    Paris, France

    14 h-index

    74 publications

    5.6K citations

  6. University of Leicester

    Leicester, United Kingdom

    14 h-index

    54 publications

    8.6K citations

  7. Vanderbilt University

    Nashville, United States

    12 h-index

    49 publications

    2.3K citations

  8. The University of Osaka

    Osaka, Japan

    12 h-index

    40 publications

    7.5K citations

1–8 of 812

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  1. Journal of Biological Chemistry

    JBC · 72 publications · 6.7K citations

    48

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  2. Journal of Cell Science

    38 publications · 4.3K citations

    32

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  3. The Journal of Cell Biology

    JCB · 34 publications · 9.3K citations

    32

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  4. Experimental Cell Research

    ECR · 20 publications · 808 citations

    17

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  5. PLoS ONE

    19 publications · 887 citations

    16

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