Concepedia

Fibrinogen Cleavage

Fibrinogen Cleavage is a biochemical process in which specific peptide bonds within the fibrinogen molecule are hydrolyzed by thrombin, thereby transforming soluble fibrinogen into insoluble fibrin monomers that polymerize to form a hemostatic clot.

939

Publications

43.8K

Citations

3.1K

Authors

858

Institutions

Publications per year

2017–2026

52

Parents

Publications

939

Thrombolysis in myocardial infarction (TIMI) trial—Phase I: Hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinase

Anupama Rao, Craig M. Pratt, Andrew Berke et al. · Journal of the American College of Cardiology · 1988 · 988 citations

, , +17

THE FIBRINOLYTIC ACTIVITY OF HEMOLYTIC STREPTOCOCCI

William S. Tillett, R. Garner · The Journal of Experimental Medicine · 1933 · 628 citations · Full text

, , +12

Measurement of Fibrinopeptide A in Human Blood

H. L. Nossel, I. Yudelman, R E Canfield et al. · Journal of Clinical Investigation · 1974 · 539 citations · Full text

, , +8

A two-step fibrinogen–fibrin transition in blood coagulation

Birger Blombäck, B. Hessel, Desmond H. Hogg et al. · Nature · 1978 · 475 citations

, , +13

Loss of Fibrinogen Rescues Mice from the Pleiotropic Effects of Plasminogen Deficiency

Thomas Bugge, Keith W. Kombrinck, Matthew J. Flick et al. · Cell · 1996 · 425 citations · Full text

, , +15

1–5 of 939

Authors

3.1K

  1. BB
    Birger Blombäck

    Karolinska Institutet, Sweden

    20 publications · 1.7K citations

    16

    h-index

  2. BH
    B. Hessel

    Karolinska Institutet, Sweden

    12 publications · 1.2K citations

    12

    h-index

  3. AZ
    Andrei Z. Budzynski

    Temple University, United States

    14 publications · 363 citations

    11

    h-index

  4. WN
    W. Nieuwenhuizen

    Netherlands Organisation for Applied Scientific Research, Netherlands

    13 publications · 687 citations

    11

    h-index

  5. EM
    Elemér Mihályi

    National Heart Lung and Blood Institute, United States

    10 publications · 384 citations

    10

    h-index

1–5 of 3.1K

Institutions

858

  1. Karolinska Institutet

    Stockholm, Sweden

    19 h-index

    74 publications

    7.6K citations

  2. Temple University

    Philadelphia, United States

    16 h-index

    73 publications

    3.6K citations

  3. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    15 h-index

    65 publications

    2.1K citations

  4. New York Blood Center

    New York, United States

    14 h-index

    55 publications

    5.2K citations

  5. Columbia University

    New York, United States

    13 h-index

    42 publications

    5.5K citations

  6. Scripps Health

    San Diego, United States

    12 h-index

    29 publications

    1.5K citations

  7. Max Planck Institute of Biochemistry

    Martinsried, Germany

    11 h-index

    31 publications

    2.2K citations

  8. Universidade de São Paulo

    São Paulo, Brazil

    11 h-index

    34 publications

    906 citations

1–8 of 858

Venues

  1. Journal of Biological Chemistry

    JBC · 62 publications · 4K citations

    37

    h-index

  2. PubMed

    Repository · 62 publications · 2.3K citations

    28

    h-index

  3. Thrombosis Research

    93 publications · 2.7K citations

    28

    h-index

  4. Biochemistry

    38 publications · 2K citations

    27

    h-index

  5. Thrombosis and Haemostasis

    53 publications · 1.9K citations

    27

    h-index

1–5