Concepedia

Factor Xii Activation

Factor XII Activation is a biochemical process in the intrinsic pathway of blood coagulation in which Factor XII undergoes a conformational change upon contact with negatively charged surfaces, distinguishing it from other zymogen activations by its unique initiation through surface-mediated autoactivation.

1.1K

Publications

61.3K

Citations

4K

Authors

978

Institutions

Publications per year

2017–2026

133

Parents

Publications

1.1K

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

Marie-Luise von Brühl, Konstantin Stark, Alexander Steinhart et al. · The Journal of Experimental Medicine · 2012 · 1.8K citations · Full text

, , +17

Factor XI Activation in a Revised Model of Blood Coagulation

David Gailani, George Broze · Science · 1991 · 780 citations

, , +10

Interaction of high molecular weight kininogen, factor XII, and fibrinogen in plasma at interfaces

Leo Vroman, Al Adams, Fischer Gc et al. · Blood · 1980 · 745 citations

, , +14

The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor

David W. Banner, A. D’Arcy, C. Chene et al. · Nature · 1996 · 733 citations

, , +15

Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation

Christian Kannemeier, Aya Shibamiya, Fumie Nakazawa et al. · Proceedings of the National Academy of Sciences · 2007 · 532 citations · Full text

, , +15

1–5 of 1.1K

Authors

4K

  1. DG
    David Gailani

    Vanderbilt University, United States

    34 publications · 3K citations

    26

    h-index

  2. RW
    Robert W. Colman

    Temple University, United States

    25 publications · 2.1K citations

    23

    h-index

  3. JH
    John H. Griffin

    Scripps Research Institute, United States

    24 publications · 2.4K citations

    20

    h-index

  4. TR
    Thomas Renné

    University Medical Center Hamburg-Eppendorf, Germany

    20 publications · 2.4K citations

    19

    h-index

  5. OD
    Oscar D. Ratnoff

    Case Western Reserve University, United States

    30 publications · 1.3K citations

    18

    h-index

1–5 of 4K

Institutions

978

  1. Temple University

    Philadelphia, United States

    29 h-index

    136 publications

    8.6K citations

  2. Vanderbilt University

    Nashville, United States

    21 h-index

    88 publications

    7.1K citations

  3. Case Western Reserve University

    Cleveland, United States

    21 h-index

    120 publications

    6.5K citations

  4. Scripps Health

    San Diego, United States

    19 h-index

    63 publications

    7.1K citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    19 h-index

    91 publications

    6.1K citations

  6. Oregon Health & Science University

    Portland, United States

    18 h-index

    99 publications

    5.8K citations

  7. University of California San Diego

    San Diego, United States

    18 h-index

    64 publications

    3.8K citations

  8. University of Washington

    Seattle, United States

    18 h-index

    48 publications

    7K citations

1–8 of 978

Venues

  1. Blood

    105 publications · 9.2K citations

    55

    h-index

  2. Journal of Biological Chemistry

    JBC · 62 publications · 5.8K citations

    43

    h-index

  3. Thrombosis and Haemostasis

    97 publications · 4K citations

    40

    h-index

  4. Journal of Clinical Investigation

    JCI · 36 publications · 3.5K citations

    29

    h-index

  5. Biochemistry

    31 publications · 2.4K citations

    28

    h-index

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