Concepedia

Exon Deletion Knockout

Exon Deletion Knockout is a gene knockout strategy that involves the precise removal of one or more exons from a target gene to disrupt its coding sequence and abolish protein function.

23

Publications

2.2K

Citations

219

Authors

99

Institutions

Publications per year

2017–2026

4

Parents

Publications

23

In vivo gene editing in dystrophic mouse muscle and muscle stem cells

Mohammadsharif Tabebordbar, Kexian Zhu, Jason Cheng et al. · Science · 2015 · 1K citations

, , +17

Preferential deletion of exons in Duchenne and Becker muscular dystrophies

S. M. Forrest, Gareth Cross, Andreas Speer et al. · Nature · 1987 · 197 citations

, , +12

Multiexon skipping leading to an artificial DMD protein lacking amino acids from exons 45 through 55 could rescue up to 63% of patients with Duchenne muscular dystrophy

Christophe Béroud, Sylvie Tuffery‐Giraud, Masafumi Matsuo et al. · Human Mutation · 2006 · 197 citations

, , +13

Identification of an Exon 4-Deletion Variant of Epidermal Growth Factor Receptor with Increased Metastasis-Promoting Capacity

Hai Wang, Min Zhou, Bizhi Shi et al. · Neoplasia · 2011 · 66 citations · Full text

, , +17

A multi-exon deletion within WWOX is associated with a 46,XY disorder of sex development

Stefan J. White, Jacqueline Hewitt, Erin Turbitt et al. · European Journal of Human Genetics · 2011 · 62 citations · Full text

, , +15

1–5 of 23

Authors

219

  1. RH
    Remko Hersmus

    Erasmus MC, Netherlands

    1 publications · 62 citations

    1

    h-index

  2. MS
    Massimo Serafini

    Ospedale Maggiore, Italy

    1 publications · 16 citations

    1

    h-index

  3. FV
    Filip Van Petegem

    University of British Columbia, Canada

    1 publications · 56 citations

    1

    h-index

  4. SL
    Stenvert L. S. Drop

    Erasmus MC - Sophia Children’s Hospital, Netherlands

    1 publications · 62 citations

    1

    h-index

  5. AJ
    Amy J. Wagers

    Harvard University, United States

    1 publications · 1K citations

    1

    h-index

1–5 of 219

Institutions

99

  1. Newcastle University

    Newcastle upon Tyne, United Kingdom

    2 h-index

    4 publications

    239 citations

  2. University of British Columbia

    Vancouver, Canada

    2 h-index

    6 publications

    274 citations

  3. University of California San Diego

    San Diego, United States

    2 h-index

    8 publications

    200 citations

  4. North Tyneside General Hospital

    North Shields, United Kingdom

    2 h-index

    3 publications

    229 citations

  5. Manchester University NHS Foundation Trust

    Manchester, United Kingdom

    1 h-index

    5 publications

    70 citations

  6. Kagoshima University

    Kagoshima, Japan

    1 h-index

    1 publications

    58 citations

  7. University of Rochester

    Rochester, United States

    1 h-index

    1 publications

    16 citations

  8. Muscular Dystrophy UK

    London, United Kingdom

    1 h-index

    2 publications

    32 citations

1–8 of 99

Venues

  1. Molecular Therapy

    2 publications · 73 citations

    2

    h-index

  2. PLoS ONE

    2 publications · 86 citations

    2

    h-index

  3. Human Genetics

    2 publications · 32 citations

    2

    h-index

  4. Carcinogenesis

    1 publications · 57 citations

    1

    h-index

  5. Nature

    1 publications · 197 citations

    1

    h-index

1–5