Concepedia

Essential Gene Characterization

Essential Gene Characterization is a methodological framework in reverse genetics that identifies and functionally annotates genes indispensable for an organism's viability or core biological processes through targeted mutagenesis and phenotypic analysis.

112

Publications

12.4K

Citations

760

Authors

228

Institutions

Publications per year

2017–2026

27

Parents

Publications

112

Identification and characterization of essential genes in the human genome

Kıvanç Birsoy, Nicholas W. Hughes, Kevin M. Krupczak et al. · Science · 2015 · 1.8K citations

, , +14

Global Transposon Mutagenesis and a Minimal Mycoplasma Genome

Clyde A. Hutchison, Scott N. Peterson, Steven R. Gill et al. · Science · 1999 · 932 citations

, , +14

A minimal gene set for cellular life derived by comparison of complete bacterial genomes.

Arcady Mushegian, Eugene V. Koonin · Proceedings of the National Academy of Sciences · 1996 · 927 citations

, , +12

Essential genes of a minimal bacterium

John I. Glass, Nacyra Assad-Garcia, Nina Alperovich et al. · Proceedings of the National Academy of Sciences · 2006 · 909 citations

, , +13

Identification of Genes Required for Embryo Development in Arabidopsis 

Iris Tzafrir, Rosanna Pena-Muralla, Allan W. Dickerman et al. · PLANT PHYSIOLOGY · 2004 · 527 citations · Full text

, , +14

1–5 of 112

Authors

760

  1. DL
    David L. Baillie

    Simon Fraser University, Canada

    6 publications · 198 citations

    6

    h-index

  2. AM
    Ann M. Rose

    University of British Columbia, Canada

    5 publications · 138 citations

    5

    h-index

  3. RJ
    Robert Johnsen

    Simon Fraser University, Canada

    4 publications · 148 citations

    4

    h-index

  4. JJ
    John J. Mekalanos

    Harvard University, United States

    3 publications · 618 citations

    3

    h-index

  5. JC
    Jeffrey Chu

    Simon Fraser University, Canada

    3 publications · 57 citations

    3

    h-index

1–5 of 760

Institutions

228

  1. Simon Fraser University

    Burnaby, Canada

    9 h-index

    22 publications

    1.1K citations

  2. University of British Columbia

    Vancouver, Canada

    6 h-index

    16 publications

    640 citations

  3. Tianjin University

    Tianjin, China

    5 h-index

    11 publications

    466 citations

  4. Harvard University

    Cambridge, United States

    5 h-index

    18 publications

    5.3K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    7 publications

    2.5K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    34 publications

    4.1K citations

  7. University of Wisconsin–Madison

    Madison, United States

    4 h-index

    18 publications

    1.7K citations

  8. Wellcome Sanger Institute

    Cambridge, United Kingdom

    3 h-index

    31 publications

    3.5K citations

1–8 of 228

Venues

  1. Journal of Bacteriology

    JB · 8 publications · 809 citations

    8

    h-index

  2. PLoS ONE

    7 publications · 449 citations

    7

    h-index

  3. Genetics

    7 publications · 413 citations

    7

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 2.7K citations

    7

    h-index

  5. BMC Genomics

    5 publications · 246 citations

    5

    h-index

1–5