Concepedia

Enzyme Binding Site Analysis

Enzyme Binding Site Analysis is a computational or experimental methodology used to characterize the specific molecular region on an enzyme where ligands interact, distinguished by its focus on identifying structural, chemical, and energetic features that govern substrate or inhibitor binding specificity and affinity.

62

Publications

3.3K

Citations

214

Authors

77

Institutions

Publications per year

2017–2026

2

Parents

Publications

62

Searching for and predicting the activity of sites for DNA binding proteins: compilation and analysis of the binding sites for<i>Escherichia coli</i>integration host factor (IHF)

James A. Goodrich, Michael L. Schwartz, William R. McClure · Nucleic Acids Research · 1990 · 286 citations · Full text

, , +14

Pigeon Liver Malic Enzyme

Robert Y. Hsu, Henry A. Lardy · Journal of Biological Chemistry · 1967 · 208 citations · Full text

, , +16

A Fluorine Scan of Thrombin Inhibitors to Map the Fluorophilicity/Fluorophobicity of an Enzyme Active Site: Evidence for CF⋅⋅⋅CO Interactions

Jacob Olsen, David W. Banner, Paul Seiler et al. · Angewandte Chemie International Edition · 2003 · 199 citations

, , +17

An Experimental Approach to Mapping the Binding Surfaces of Crystalline Proteins

Karen N. Allen, Cornelia Bellamacina, Xiaochun Ding et al. · The Journal of Physical Chemistry · 1996 · 190 citations

, , +13

Methidiumpropyl-EDTA-Fe(II) and DNase I footprinting report different small molecule binding site sizes on DNA

Michael W. Van Dyke, Peter B. Dervan · Nucleic Acids Research · 1983 · 175 citations · Full text

, , +13

1–5 of 62

Authors

214

  1. RY
    Robert Y. Hsu

    SUNY Upstate Medical University, United States

    3 publications · 379 citations

    3

    h-index

  2. HA
    Henry A. Lardy

    University of Wisconsin–Madison, United States

    3 publications · 379 citations

    3

    h-index

  3. PS
    Paul Seiler

    ETH Zurich, Switzerland

    2 publications · 278 citations

    2

    h-index

  4. AD
    A. D’Arcy

    Roche (Switzerland), Switzerland

    2 publications · 278 citations

    2

    h-index

  5. DW
    David W. Banner

    Roche (Switzerland), Switzerland

    2 publications · 278 citations

    2

    h-index

1–5 of 214

Institutions

77

  1. University of Wisconsin–Madison

    Madison, United States

    4 h-index

    9 publications

    899 citations

  2. Inserm

    Paris, France

    4 h-index

    16 publications

    870 citations

  3. National Institutes of Health

    Bethesda, United States

    3 h-index

    6 publications

    229 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    10 publications

    762 citations

  5. National Eye Institute

    Bethesda, United States

    2 h-index

    8 publications

    265 citations

  6. Max Planck Society

    Munich, Germany

    2 h-index

    4 publications

    82 citations

  7. North Dakota State University

    Fargo, United States

    2 h-index

    8 publications

    412 citations

  8. Roche (Switzerland)

    Basel, Switzerland

    2 h-index

    10 publications

    1.4K citations

1–8 of 77

Venues

  1. Biochemistry

    12 publications · 428 citations

    11

    h-index

  2. Journal of Biological Chemistry

    JBC · 6 publications · 472 citations

    6

    h-index

  3. Bioorganic & Medicinal Chemistry

    4 publications · 127 citations

    4

    h-index

  4. Nucleic Acids Research

    3 publications · 495 citations

    3

    h-index

  5. Journal of Molecular Biology

    JMB · 3 publications · 152 citations

    3

    h-index

1–5