Concepedia

Enthalpy Compensation

Enthalpy Compensation is a thermodynamic phenomenon in multivalent interactions wherein a favorable enthalpic contribution is offset by an accompanying unfavorable entropic change, resulting in a minimal net change in binding free energy.

227

Publications

11.9K

Citations

757

Authors

297

Institutions

Publications per year

2017–2026

38

Parents

Publications

227

Enthalpy-entropy compensation. 2. Separation of the chemical from the statistical effect

Russell R. Krug, William G. Hunter, R. A. Grieger · The Journal of Physical Chemistry · 1976 · 804 citations

, , +11

Enthalpy-entropy compensation. 1. Some fundamental statistical problems associated with the analysis of van't Hoff and Arrhenius data

Russell R. Krug, William G. Hunter, R. A. Grieger · The Journal of Physical Chemistry · 1976 · 718 citations

, , +16

Entropy—enthalpy compensation: Fact or artifact?

Kim A. Sharp · Protein Science · 2001 · 420 citations · Full text

, , +17

Water Networks Contribute to Enthalpy/Entropy Compensation in Protein–Ligand Binding

Benjamin Breiten, Matthew R. Lockett, Woody Sherman et al. · Journal of the American Chemical Society · 2013 · 332 citations · Full text

, , +17

Heat does not come in different colours: entropy–enthalpy compensation, free energy windows, quantum confinement, pressure perturbation calorimetry, solvation and the multiple causes of heat capacity effects in biomolecular interactions

Alan Cooper, C. Mark Johnson, Jeremy H. Lakey et al. · Biophysical Chemistry · 2001 · 331 citations

, , +17

1–5 of 227

Authors

757

  1. FM
    Fleming Martínez

    Universidad Nacional de Colombia, Colombia

    5 publications · 359 citations

    5

    h-index

  2. AK
    Animesh Kumar Rakshit

    Maharaja Sayajirao University of Baroda, India

    5 publications · 277 citations

    5

    h-index

  3. JF
    Jack F. Douglas

    National Institute of Standards and Technology, United States

    5 publications · 218 citations

    5

    h-index

  4. EB
    E. B. Starikov

    Freie Universität Berlin, Germany

    4 publications · 149 citations

    4

    h-index

  5. SP
    Satya P. Moulik

    Jadavpur University, India

    3 publications · 233 citations

    3

    h-index

1–5 of 757

Institutions

297

  1. National Institute of Standards and Technology

    Gaithersburg, United States

    6 h-index

    12 publications

    337 citations

  2. University of Cambridge

    Cambridge, United Kingdom

    5 h-index

    9 publications

    448 citations

  3. Universidad Nacional de Colombia

    Bogotá, Colombia

    5 h-index

    14 publications

    682 citations

  4. Universidad de Alcalá

    Alcalá de Henares, Spain

    4 h-index

    8 publications

    609 citations

  5. Chalmers University of Technology

    Gothenburg, Sweden

    4 h-index

    6 publications

    247 citations

  6. University of Copenhagen

    Copenhagen, Denmark

    4 h-index

    16 publications

    399 citations

  7. National Taiwan University

    Taipei, Taiwan

    4 h-index

    19 publications

    1.1K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    17 publications

    744 citations

1–8 of 297

Venues

  1. Biochemistry

    15 publications · 783 citations

    15

    h-index

  2. The Journal of Physical Chemistry B

    15 publications · 638 citations

    13

    h-index

  3. Journal of the American Chemical Society

    JACS · 10 publications · 1K citations

    10

    h-index

  4. The Journal of Chemical Physics

    9 publications · 368 citations

    9

    h-index

  5. The Journal of Physical Chemistry

    6 publications · 1.9K citations

    6

    h-index

1–5