Concepedia

Enhancer Turnover

Enhancer Turnover is a genomic phenomenon characterized by the evolutionary replacement of ancestral enhancer elements with new regulatory sequences that maintain or alter gene expression patterns across related species.

12

Publications

906

Citations

61

Authors

35

Institutions

Publications per year

2017–2026

6

Parents

Publications

12

Quantitative genome-wide enhancer activity maps for five Drosophila species show functional enhancer conservation and turnover during cis-regulatory evolution

Cosmas D. Arnold, Daniel Gerlach, Daniel Spies et al. · Nature Genetics · 2014 · 198 citations · Full text

, , +17

Enhancer regions show high histone H3.3 turnover that changes during differentiation

Aimée M. Deaton, Mariluz Gómez Rodríguez, Jakub Mieczkowski et al. · eLife · 2016 · 109 citations · Full text

, , +17

Prediction of gene regulatory enhancers across species reveals evolutionarily conserved sequence properties

Alexandra E. Fish, John A. Capra · PLoS Computational Biology · 2018 · 106 citations · Full text

, , +17

Functional characterization of enhancer evolution in the primate lineage

Jason C. Klein, Aidan Keith, Vikram Agarwal et al. · Genome biology · 2018 · 72 citations · Full text

, , +16

The frequent evolutionary birth and death of functional promoters in mouse and human

Robert S. Young, Yoshihide Hayashizaki, Robin Andersson et al. · Genome Research · 2015 · 70 citations · Full text

, , +15

1–5 of 12

Authors

61

  1. RS
    Robert S. Young

    Institute of Genetics and Cancer, United Kingdom

    2 publications · 136 citations

    2

    h-index

  2. AE
    Alexandra E. Fish

    Vanderbilt University, United States

    2 publications · 150 citations

    2

    h-index

  3. JA
    John A. Capra

    Vanderbilt University, United States

    2 publications · 150 citations

    2

    h-index

  4. WA
    Wendy A. Bickmore

    Institute of Genetics and Cancer, United Kingdom

    2 publications · 136 citations

    2

    h-index

  5. MS
    Martin S. Taylor

    University of Edinburgh, United Kingdom

    1 publications · 70 citations

    1

    h-index

1–5 of 61

Institutions

35

  1. Vanderbilt University

    Nashville, United States

    2 h-index

    6 publications

    450 citations

  2. University of Edinburgh

    Edinburgh, United Kingdom

    2 h-index

    7 publications

    474 citations

  3. Institute of Genetics and Cancer

    Edinburgh, United Kingdom

    2 h-index

    6 publications

    408 citations

  4. University of Michigan

    Ann Arbor, United States

    1 h-index

    1 publications

    45 citations

  5. The Gurdon Institute

    Cambridge, United Kingdom

    1 h-index

    1 publications

    65 citations

  6. Instituto Gulbenkian de Ciência

    Oeiras, Portugal

    1 h-index

    2 publications

    218 citations

  7. George Washington University

    Washington, United States

    1 h-index

    3 publications

    180 citations

  8. Roslin Institute

    Dalkeith, United Kingdom

    1 h-index

    2 publications

    132 citations

1–8 of 35

Venues

  1. eLife

    1 publications · 109 citations

    1

    h-index

  2. Molecular Biology and Evolution

    MBE · 1 publications · 42 citations

    1

    h-index

  3. 1

    h-index

  4. The Journal of Immunology

    JI · 1 publications · 66 citations

    1

    h-index

  5. Science

    1 publications · 60 citations

    1

    h-index

1–5