Concepedia

Enhancer Priming

Enhancer Priming is a molecular mechanism in gene regulation whereby specific chromatin modifications and transcription factor binding at enhancer regions establish a transcriptionally permissive state that precedes and facilitates subsequent gene activation in response to developmental or environmental cues.

18

Publications

2.2K

Citations

150

Authors

60

Institutions

Publications per year

2017–2026

12

Parents

Publications

18

Shared genetic effects on chromatin and gene expression indicate a role for enhancer priming in immune response

Kaur Alasoo, Julia Rodrigues, Subhankar Mukhopadhyay et al. · Nature Genetics · 2018 · 411 citations · Full text

, , +17

Epigenetic Priming of Enhancers Predicts Developmental Competence of hESC-Derived Endodermal Lineage Intermediates

Allen Wang, Feng Yue, Yan Li et al. · Cell stem cell · 2015 · 290 citations · Full text

, , +16

Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition

Chaochen Wang, Ji‐Eun Lee, Binbin Lai et al. · Proceedings of the National Academy of Sciences · 2016 · 243 citations · Full text

, , +17

Zelda overcomes the high intrinsic nucleosome barrier at enhancers during <i>Drosophila</i> zygotic genome activation

Yujia Sun, Chung-Yi Nien, Kai Chen et al. · Genome Research · 2015 · 208 citations · Full text

, , +17

Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs

Jérémy Dufourt, Antonio Trullo, Jennifer Hunter et al. · Nature Communications · 2018 · 169 citations · Full text

, , +17

1–5 of 18

Authors

150

  1. FY
    Feng Yue

    Pennsylvania State University, United States

    2 publications · 340 citations

    2

    h-index

  2. DK
    Dieter K. Lam

    Beam Therapeutics (United States), United States

    2 publications · 355 citations

    2

    h-index

  3. MS
    Maike Sander

    University of California San Diego, United States

    2 publications · 355 citations

    2

    h-index

  4. AW
    Allen Wang

    University of California San Diego, United States

    2 publications · 355 citations

    2

    h-index

  5. JW
    Jinzhao Wang

    University of California San Diego, United States

    2 publications · 355 citations

    2

    h-index

1–5 of 150

Institutions

60

  1. University of California San Diego

    San Diego, United States

    2 h-index

    22 publications

    3.7K citations

  2. Sanford Consortium for Regenerative Medicine

    La Jolla, United States

    2 h-index

    17 publications

    3.1K citations

  3. Ludwig Cancer Research

    New York, United States

    2 h-index

    4 publications

    935 citations

  4. Wellcome Sanger Institute

    Cambridge, United Kingdom

    2 h-index

    18 publications

    3.8K citations

  5. University of Cambridge

    Cambridge, United Kingdom

    2 h-index

    3 publications

    671 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    18 publications

    2.2K citations

  7. Cornell University

    Ithaca, United States

    2 h-index

    3 publications

    376 citations

  8. Friedrich Miescher Institute

    Basel, Switzerland

    1 h-index

    4 publications

    200 citations

1–8 of 60

Venues

  1. Nature Communications

    3 publications · 284 citations

    3

    h-index

  2. Molecular Cell

    2 publications · 118 citations

    2

    h-index

  3. Cell Reports

    2 publications · 202 citations

    2

    h-index

  4. Genome Research

    GR · 2 publications · 252 citations

    2

    h-index

  5. Cell stem cell

    2 publications · 378 citations

    2

    h-index

1–5