Concepedia

Enhancer Interactions

Enhancer Interactions is a molecular regulatory phenomenon in which distal cis-regulatory DNA sequences (enhancers) spatially and functionally engage with target gene promoters through chromatin looping and transcription factor mediation to modulate gene expression specificity, magnitude, and timing.

353

Publications

37.8K

Citations

2.5K

Authors

520

Institutions

Publications per year

2017–2026

94

Parents

Publications

353

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

Ranjan Sen, David Baltimore · Cell · 1986 · 2.8K citations · Full text

, , +13

Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions

Darío G. Lupiáñez, Katerina Kraft, Verena Heinrich et al. · Cell · 2015 · 2.3K citations · Full text

, , +12

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

Amy T. Hark, Christopher J. Schoenherr, David J. Katz et al. · Nature · 2000 · 1.5K citations

, , +14

The long-range interaction landscape of gene promoters

Amartya Sanyal, Bryan R. Lajoie, Gaurav Jain et al. · Nature · 2012 · 1.5K citations · Full text

, , +17

Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters

Biola M. Javierre, Oliver S. Burren, Steven P. Wilder et al. · Cell · 2016 · 1.2K citations · Full text

, , +17

1–5 of 353

Authors

2.5K

  1. RC
    Reid C. Johnson

    University of California, Los Angeles, United States

    8 publications · 666 citations

    8

    h-index

  2. KC
    Kathryn Calame

    Columbia University, United States

    6 publications · 266 citations

    6

    h-index

  3. JP
    James P. Whitlock

    Stanford University, United States

    5 publications · 982 citations

    5

    h-index

  4. LH
    Lothar Hennighausen

    National Institute of Diabetes and Digestive and Kidney Diseases, United States

    5 publications · 252 citations

    5

    h-index

  5. SS
    Stefan Schoenfelder

    Babraham Institute, United Kingdom

    4 publications · 459 citations

    4

    h-index

1–5 of 2.5K

Institutions

520

  1. National Institutes of Health

    Bethesda, United States

    18 h-index

    85 publications

    7.1K citations

  2. Harvard University

    Cambridge, United States

    16 h-index

    56 publications

    4.4K citations

  3. Stanford University

    Stanford, United States

    14 h-index

    93 publications

    12.9K citations

  4. University of California San Diego

    San Diego, United States

    13 h-index

    59 publications

    10.2K citations

  5. University of California, Los Angeles

    Los Angeles, United States

    13 h-index

    47 publications

    4.4K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    12 h-index

    57 publications

    21.7K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    55 publications

    4.5K citations

  8. Weizmann Institute of Science

    Rehovot, Israel

    7 h-index

    24 publications

    872 citations

1–8 of 520

Venues

  1. Nucleic Acids Research

    42 publications · 1.9K citations

    28

    h-index

  2. Journal of Biological Chemistry

    JBC · 34 publications · 2.5K citations

    26

    h-index

  3. Molecular and Cellular Biology

    MCB · 33 publications · 2.2K citations

    24

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 24 publications · 2.8K citations

    22

    h-index

  5. Genes & Development

    13 publications · 2.2K citations

    13

    h-index

1–5