Concepedia

Enhancer Design

Enhancer Design is a computational or experimental methodology within synthetic gene design that specifies the construction and optimization of DNA sequences to augment transcriptional activity in a spatiotemporal or condition-specific manner.

177

Publications

15.7K

Citations

967

Authors

304

Institutions

Publications per year

2017–2026

40

Parents

Publications

177

In vivo enhancer analysis of human conserved non-coding sequences

L Pennacchio, Nadav Ahituv, Alan M Moses et al. · Nature · 2006 · 1.2K citations · Full text

, , +11

Learning a Deep Single Image Contrast Enhancer from Multi-Exposure Images

Jianrui Cai, Shuhang Gu, Lei Zhang · IEEE Transactions on Image Processing · 2018 · 1.2K citations

, , +16

Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay

Alexandre Melnikov, Anand Murugan, Xiaolan Zhang et al. · Nature Biotechnology · 2012 · 776 citations

, , +12

Functional annotation of native enhancers with a Cas9–histone demethylase fusion

Nicola A. Kearns, Hannah Pham, Barbara Tabak et al. · Nature Methods · 2015 · 651 citations · Full text

, , +16

Scanning Human Gene Deserts for Long-Range Enhancers

Marcelo A. Nóbrega, Ivan Ovcharenko, Veena Afzal et al. · Science · 2003 · 601 citations · Full text

, , +10

1–5 of 177

Authors

967

  1. VA
    Veena Afzal

    Lawrence Berkeley National Laboratory, United States

    5 publications · 2K citations

    5

    h-index

  2. AS
    Alexander Stark

    Research Institute of Molecular Pathology, Austria

    4 publications · 491 citations

    4

    h-index

  3. LP
    L Pennacchio

    Lawrence Berkeley National Laboratory, United States

    4 publications · 1.4K citations

    4

    h-index

  4. EM
    Edward M. Rubin

    Lawrence Berkeley National Laboratory, United States

    4 publications · 1.9K citations

    4

    h-index

  5. MP
    Michaela Pagani

    Research Institute of Molecular Pathology, Austria

    4 publications · 491 citations

    4

    h-index

1–5 of 967

Institutions

304

  1. Harvard University

    Cambridge, United States

    11 h-index

    61 publications

    4.8K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    14 publications

    1.4K citations

  3. Joint Genome Institute

    Berkeley, United States

    5 h-index

    19 publications

    8K citations

  4. The University of Texas Southwestern Medical Center

    Dallas, United States

    5 h-index

    23 publications

    2.6K citations

  5. Lawrence Berkeley National Laboratory

    Berkeley, United States

    5 h-index

    50 publications

    24.3K citations

  6. University of Pennsylvania

    Philadelphia, United States

    4 h-index

    16 publications

    503 citations

  7. Albert Einstein College of Medicine

    Bronx, United States

    4 h-index

    13 publications

    630 citations

  8. University of California, San Francisco

    San Francisco, United States

    4 h-index

    13 publications

    2.8K citations

1–8 of 304

Venues

  1. Journal of Biological Chemistry

    JBC · 10 publications · 816 citations

    10

    h-index

  2. Nucleic Acids Research

    12 publications · 942 citations

    10

    h-index

  3. The EMBO Journal

    7 publications · 859 citations

    7

    h-index

  4. Cell

    6 publications · 1.1K citations

    6

    h-index

  5. Developmental Biology

    5 publications · 296 citations

    5

    h-index

1–5