Alexandre Melnikov

Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes

Adrian L. Sanborn, Suhas S.P. Rao, Su-Chen Huang et al. · Proceedings of the National Academy of Sciences · 2015 · 1.9K citations · Full text

Protein Assembly, Genetics, Genomic Mechanism +26

Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing

Andreas Gnirke, Alexandre Melnikov, Jared Maguire et al. · Nature Biotechnology · 2009 · 1.5K citations · Full text

Engineering, Genetics, Molecular Biology +16

Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay

Alexandre Melnikov, Anand Murugan, Xiaolan Zhang et al. · Nature Biotechnology · 2012 · 748 citations

Parallel Reporter, Systems Biology, Reporter Gene Assay +9

Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits

Jacob C. Ulirsch, Satish K. Nandakumar, Li Wang et al. · Cell · 2016 · 365 citations · Full text

Biology, Genetic Analysis, Allelic Variant +9

Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay

Pouya Kheradpour, Jason Ernst, Alexandre Melnikov et al. · Genome Research · 2013 · 352 citations · Full text