Concepedia

Enhancer Core Architecture

Enhancer Core Architecture is a conceptual framework within genomics that specifies the minimal functional organization of cis-regulatory elements defining an enhancer, distinguished by its essential sequence motifs, spatial configuration, and transcription factor binding requirements necessary for cell-type-specific gene regulation.

245

Publications

20.3K

Citations

1.1K

Authors

322

Institutions

Publications per year

2017–2026

24

Parents

Publications

245

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

Hans Weiher, Monika König · Science · 1983 · 877 citations

, , +16

Complex multi-enhancer contacts captured by genome architecture mapping

Robert A. Beagrie, Antonio Scialdone, Markus Schueler et al. · Nature · 2017 · 763 citations · Full text

, , +13

The "beta-like-globin" gene domain in human erythroid cells.

Dorothy Tuan, William B. Solomon, Q Li et al. · Proceedings of the National Academy of Sciences · 1985 · 623 citations · Full text

, , +12

Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements

Maxwell R. Mumbach, Ansuman T. Satpathy, Evan A. Boyle et al. · Nature Genetics · 2017 · 556 citations · Full text

, , +14

Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions.

Samuel P. Meyers, James R. Downing, Scott W. Hiebert · Molecular and Cellular Biology · 1993 · 474 citations · Full text

, , +14

1–5 of 245

Authors

1.1K

  1. NA
    Nancy A. Speck

    Dartmouth College, United States

    5 publications · 473 citations

    5

    h-index

  2. HK
    Hisato Kondoh

    The University of Osaka, Japan

    4 publications · 258 citations

    4

    h-index

  3. ML
    Michael L. Atchison

    University of Pennsylvania, United States

    4 publications · 212 citations

    4

    h-index

  4. EE
    Edward E. Max

    National Institute of Allergy and Infectious Diseases, United States

    4 publications · 251 citations

    4

    h-index

  5. JR
    James R. Downing

    St. Jude Children's Research Hospital, United States

    4 publications · 1.1K citations

    4

    h-index

1–5 of 1.1K

Institutions

322

  1. University of Pennsylvania

    Philadelphia, United States

    13 h-index

    30 publications

    2K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    12 h-index

    33 publications

    3.4K citations

  3. National Institutes of Health

    Bethesda, United States

    11 h-index

    32 publications

    5.4K citations

  4. Harvard University

    Cambridge, United States

    10 h-index

    51 publications

    5.1K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    35 publications

    2.4K citations

  6. Inserm

    Paris, France

    8 h-index

    43 publications

    2.8K citations

  7. Massachusetts Institute of Technology

    Cambridge, United States

    7 h-index

    21 publications

    2.8K citations

  8. University of Michigan

    Ann Arbor, United States

    6 h-index

    17 publications

    1.9K citations

1–8 of 322

Venues

  1. Molecular and Cellular Biology

    MCB · 52 publications · 3.6K citations

    34

    h-index

  2. Journal of Biological Chemistry

    JBC · 37 publications · 2.1K citations

    26

    h-index

  3. Journal of Virology

    JVI · 19 publications · 1.2K citations

    17

    h-index

  4. Nucleic Acids Research

    12 publications · 458 citations

    11

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 1.9K citations

    8

    h-index

1–5