Nancy A. Speck

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.

Qing Wang, Terryl Stacy, Michael Binder et al. · Proceedings of the National Academy of Sciences · 1996 · 1.2K citations · Full text

Genetics, Immunology, Blood Cell +20

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

Woo‐Joo Song, Melanie G. Sullivan, Robert D. Legare et al. · Nature Genetics · 1999 · 1.1K citations

Hematological Malignancy, Thrombosis, Acute Myelogenous Leukaemia +11

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

Michael Chen, Tomomasa Yokomizo, Brandon M. Zeigler et al. · Nature · 2009 · 986 citations · Full text

Endothelial Cell Pathobiology, Developmental Biology, Angiogenesis +9

<i>Cbfa2</i> is required for the formation of intra-aortic hematopoietic clusters

Trista E. North, Ting‐Lei Gu, Terryl Stacy et al. · Development · 1999 · 648 citations

The CBFβ Subunit Is Essential for CBFα2 (AML1) Function In Vivo

Qing Wang, Terryl Stacy, Janelle Miller et al. · Cell · 1996 · 623 citations · Full text