Concepedia

Endosomal Retention

Endosomal Retention is a biological phenomenon characterized by the confinement of internalized molecules or delivery systems within endosomes, preventing their release into the cytoplasm due to failure in endosomal membrane disruption or trafficking escape mechanisms.

269

Publications

20.4K

Citations

1.6K

Authors

505

Institutions

Publications per year

2017–2026

96

Parents

Publications

269

Chloride Accumulation and Swelling in Endosomes Enhances DNA Transfer by Polyamine-DNA Polyplexes

N.D. Sonawane, Francis C. Szoka, A.S. Verkman · Journal of Biological Chemistry · 2003 · 1.1K citations · Full text

, , +14

Movement of internalized ligand–receptor complexes along a continuous endosomal reticulum

Colin R. Hopkins, Adele Gibson, M. Shipman et al. · Nature · 1990 · 424 citations

, , +14

Carriers Break Barriers in Drug Delivery: Endocytosis and Endosomal Escape of Gene Delivery Vectors

Isabelle M. S. Degors, Cuifeng Wang, Zia Ur Rehman et al. · Accounts of Chemical Research · 2019 · 416 citations · Full text

, , +17

Cytokine Activation Leads to Acidification and Increases Maturation of <i>Mycobacterium avium</i> -Containing Phagosomes in Murine Macrophages

Ulrich E. Schaible, Sheila Sturgill-Koszycki, Paul H. Schlesinger et al. · The Journal of Immunology · 1998 · 402 citations · Full text

, , +17

Polyplexes from Poly(aspartamide) Bearing 1,2-Diaminoethane Side Chains Induce pH-Selective, Endosomal Membrane Destabilization with Amplified Transfection and Negligible Cytotoxicity

Kanjiro Miyata, Makoto Oba, Masataka Nakanishi et al. · Journal of the American Chemical Society · 2008 · 370 citations

, , +14

1–5 of 269

Authors

1.6K

  1. KN
    Kristina Najjar

    Texas A&M University, United States

    5 publications · 469 citations

    5

    h-index

  2. AE
    Alfredo Erazo‐Oliveras

    Texas A&M University, United States

    5 publications · 469 citations

    5

    h-index

  3. KB
    Kevin Braeckmans

    Ghent University, Belgium

    4 publications · 441 citations

    4

    h-index

  4. SF
    Shiroh Futaki

    Kyoto University, Japan

    4 publications · 191 citations

    4

    h-index

  5. LL
    Lennart Lindfors

    AstraZeneca (Sweden), Sweden

    2 publications · 206 citations

    3

    h-index

1–5 of 1.6K

Institutions

505

  1. Inserm

    Paris, France

    12 h-index

    47 publications

    2.1K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    60 publications

    8.7K citations

  3. National Institutes of Health

    Bethesda, United States

    8 h-index

    17 publications

    1.7K citations

  4. Texas A&M University

    College Station, United States

    7 h-index

    43 publications

    3.3K citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    6 h-index

    15 publications

    492 citations

  6. University of Washington

    Seattle, United States

    6 h-index

    34 publications

    2.8K citations

  7. University of California, San Francisco

    San Francisco, United States

    6 h-index

    23 publications

    4.4K citations

  8. Kyoto University

    Kyoto, Japan

    6 h-index

    22 publications

    899 citations

1–8 of 505

Venues

  1. Journal of Biological Chemistry

    JBC · 19 publications · 2.4K citations

    17

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 11 publications · 1K citations

    11

    h-index

  3. PLoS ONE

    9 publications · 313 citations

    9

    h-index

  4. ACS Nano

    8 publications · 1K citations

    8

    h-index

  5. Bioconjugate Chemistry

    7 publications · 433 citations

    7

    h-index

1–5