Concepedia

Endogenous Substrate Conjugation

Endogenous Substrate Conjugation is a biochemical process in which an endogenous substrate undergoes covalent modification through the attachment of a polar conjugating agent, typically mediated by specific transferase enzymes, to enhance its water solubility and facilitate excretion.

36

Publications

2.4K

Citations

152

Authors

51

Institutions

Publications per year

2017–2026

1

Parents

Publications

36

Phosphatidylserine in Addition to Phosphatidylethanolamine Is an in Vitro Target of the Mammalian Atg8 Modifiers, LC3, GABARAP, and GATE-16

Yu‐shin Sou, Isei Tanida, Masaaki Komatsu et al. · Journal of Biological Chemistry · 2005 · 198 citations · Full text

, , +11

Substrate specificity of human aldose reductase: identification of 4-hydroxynonenal as an endogenous substrate

David L. bander Jagt, Natasha S. Kolb, Timothy J. bander Jagt et al. · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · 1995 · 182 citations

, , +8

Purification and identification of endogenous polySUMO conjugates

Roland Bruderer, Michael H. Tatham, Anna Plechanovová et al. · EMBO Reports · 2011 · 165 citations · Full text

, , +5

Regeneration of serotonin from 5-methoxytryptamine by polymorphic human CYP2D6.

Ai‐Ming Yu, Jeffrey R. Idle, Linda G. Byrd et al. · PubMed · 2003 · 160 citations

, , +17

An endogenous substrate for cGMP-dependent protein kinase in mammalian cerebellum

D Schlichter, J E Casnellie, Paul Greengard · Nature · 1978 · 157 citations

, , +12

1–5 of 36

Authors

152

  1. IT
    Isei Tanida

    Juntendo University, Japan

    3 publications · 288 citations

    3

    h-index

  2. MK
    Masaaki Komatsu

    Tokyo Metropolitan Institute of Medical Science, Japan

    2 publications · 253 citations

    2

    h-index

  3. YS
    Yu‐shin Sou

    Juntendo University, Japan

    2 publications · 233 citations

    2

    h-index

  4. EK
    Eiki Kominami

    Juntendo University, Japan

    2 publications · 233 citations

    2

    h-index

  5. LA
    Lucy A. Hunsaker

    University of New Mexico, United States

    1 publications · 182 citations

    1

    h-index

1–5 of 152

Institutions

51

  1. University of Dundee

    Dundee, United Kingdom

    2 h-index

    4 publications

    460 citations

  2. United States Department of Veterans Affairs

    Washington, United States

    2 h-index

    4 publications

    202 citations

  3. Juntendo University

    Tokyo, Japan

    2 h-index

    6 publications

    1K citations

  4. University of Pittsburgh

    Pittsburgh, United States

    2 h-index

    21 publications

    2.2K citations

  5. Middlesex Hospital

    Middletown, United States

    1 h-index

    3 publications

    30 citations

  6. Institut Pasteur de Montevideo

    Montevideo, Uruguay

    1 h-index

    1 publications

    147 citations

  7. Cell and Gene Therapy Catapult

    London, United Kingdom

    1 h-index

    5 publications

    825 citations

  8. Johns Hopkins University

    Baltimore, United States

    1 h-index

    2 publications

    192 citations

1–8 of 51

Venues

  1. Journal of Biological Chemistry

    JBC · 4 publications · 504 citations

    4

    h-index

  2. PubMed

    Repository · 2 publications · 200 citations

    2

    h-index

  3. Archives of Biochemistry and Biophysics

    ABB · 2 publications · 70 citations

    2

    h-index

  4. Biochemical Journal

    BJ · 2 publications · 183 citations

    2

    h-index

  5. Autophagy

    2 publications · 90 citations

    2

    h-index

1–5