Concepedia

Endogenous Antigen Processing

Endogenous Antigen Processing is the intracellular pathway by which self-synthesized antigens, such as viral or tumor proteins, are degraded by the proteasome, transported into the endoplasmic reticulum via the TAP transporter, and loaded onto major histocompatibility complex class I molecules for presentation to cytotoxic T cells.

138

Publications

10.8K

Citations

785

Authors

252

Institutions

Publications per year

2017–2026

6

Variants

Mhc Class I Pathway

Parents

Publications

138

MHC Class I Expression in Mice Lacking the Proteasome Subunit LMP-7

Hans Jörg Fehling, Wojciech Swat, Catherine Laplace et al. · Science · 1994 · 527 citations

, , +17

Quantitating Protein Synthesis, Degradation, and Endogenous Antigen Processing

Michael F. Princiotta, Diana Finzi, Shu‐Bing Qian et al. · Immunity · 2003 · 523 citations · Full text

, , +14

Class I-restricted processing and presentation of exogenous cell-associated antigen in vivo.

Federico Carbone, Michael J. Bevan · The Journal of Experimental Medicine · 1990 · 407 citations · Full text

, , +17

Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

Sven Burgdorf, Christian Schölz, Andreas Kautz et al. · Nature Immunology · 2008 · 397 citations

, , +14

Major histocompatibility complex class II‐restricted presentation of a cytosolic antigen by autophagy

Falk Nimmerjahn, Slavoljub Milosevic, Uta Behrends et al. · European Journal of Immunology · 2003 · 349 citations · Full text

, , +17

1–5 of 138

Authors

785

  1. RK
    Rajiv Khanna

    QIMR Berghofer Medical Research Institute, Australia

    7 publications · 642 citations

    7

    h-index

  2. JT
    Judy Tellam

    QIMR Berghofer Medical Research Institute, Australia

    5 publications · 336 citations

    5

    h-index

  3. JR
    Jack R. Bennink

    National Institute of Allergy and Infectious Diseases, United States

    4 publications · 776 citations

    4

    h-index

  4. SR
    Scott R. Burrows

    QIMR Berghofer Medical Research Institute, Australia

    4 publications · 491 citations

    4

    h-index

  5. AB
    Alan B. Rickinson

    University of Birmingham, United Kingdom

    4 publications · 438 citations

    4

    h-index

1–5 of 785

Institutions

252

  1. Harvard University

    Cambridge, United States

    9 h-index

    22 publications

    2.1K citations

  2. QIMR Berghofer Medical Research Institute

    Brisbane, Australia

    7 h-index

    41 publications

    3.6K citations

  3. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    6 h-index

    29 publications

    5.1K citations

  4. University of Birmingham

    Birmingham, United Kingdom

    6 h-index

    17 publications

    2.3K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    13 publications

    1.9K citations

  6. Leiden University Medical Center

    Leiden, The Netherlands

    5 h-index

    26 publications

    2.2K citations

  7. National Institutes of Health

    Bethesda, United States

    5 h-index

    28 publications

    1.5K citations

  8. Charité - Universitätsmedizin Berlin

    Berlin, Germany

    5 h-index

    25 publications

    3.2K citations

1–8 of 252

Venues

  1. The Journal of Experimental Medicine

    16 publications · 2.2K citations

    15

    h-index

  2. European Journal of Immunology

    EJI · 15 publications · 1.3K citations

    14

    h-index

  3. The Journal of Immunology

    JI · 11 publications · 874 citations

    11

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 10 publications · 872 citations

    10

    h-index

  5. PubMed

    Repository · 9 publications · 339 citations

    9

    h-index

1–5