Concepedia

Electrophile Detoxification

Electrophile Detoxification is a biochemical process in which electrophilic compounds are neutralized through covalent conjugation with glutathione, thereby reducing their reactivity and facilitating their elimination from the cell.

19

Publications

1.1K

Citations

78

Authors

26

Institutions

Publications per year

2017–2026

2

Parents

Publications

19

The quinone reductase gene: A unique estrogen receptor-regulated gene that is activated by antiestrogens

Monica M. Montano, Benita S. Katzenellenbogen · Proceedings of the National Academy of Sciences · 1997 · 164 citations

, , +15

Thioredoxin-dependent redox regulation of the antioxidant responsive element (ARE) in electrophile response

Yong‐Chul Kim, Yoshimi Yamaguchi, Norihiko Kondo et al. · Oncogene · 2003 · 130 citations

, , +16

Construction and characterization of Escherichia coli genetically engineered for bioremediation of Hg(2+)-contaminated environments

Sixue Chen, David B. Wilson · Applied and Environmental Microbiology · 1997 · 115 citations · Full text

, , +17

Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer l,2-dithiole-3-thione

Thomas W. Kensler, John D. Groopman, David L. Eaton et al. · Carcinogenesis · 1992 · 98 citations

, , +14

Evolved Stereoselective Hydrolases for Broad-Spectrum G-Type Nerve Agent Detoxification

Moshe Goldsmith, Yacov Ashani, Yair Simo et al. · Chemistry & Biology · 2012 · 95 citations

, , +12

1–5 of 19

Authors

78

  1. TP
    Tarmo P. Roosild

    Salk Institute for Biological Studies, United States

    1 publications · 82 citations

    1

    h-index

  2. DL
    David L. Eaton

    University of Washington, United States

    1 publications · 98 citations

    1

    h-index

  3. DB
    David B. Wilson

    Cornell University, United States

    1 publications · 115 citations

    1

    h-index

  4. RV
    Rachapudi Venkata Sreeharsha

    University of Hyderabad, India

    1 publications · 15 citations

    1

    h-index

  5. SA
    Sanjay Awasthi

    The University of Texas Medical Branch at Galveston, United States

    1 publications · 48 citations

    1

    h-index

1–5 of 78

Institutions

26

  1. Johns Hopkins University

    Baltimore, United States

    2 h-index

    6 publications

    532 citations

  2. The University of Queensland

    Brisbane, Australia

    1 h-index

    4 publications

    144 citations

  3. Cornell University

    Ithaca, United States

    1 h-index

    2 publications

    230 citations

  4. University of St Andrews

    St Andrews, United Kingdom

    1 h-index

    1 publications

    82 citations

  5. Southwest Forestry University

    Kunming, China

    1 h-index

    1 publications

    21 citations

  6. University of Aberdeen

    Aberdeen, United Kingdom

    1 h-index

    6 publications

    492 citations

  7. Hanover College

    Hanover, United States

    1 h-index

    1 publications

    98 citations

  8. Kyoto University

    Kyoto, Japan

    1 h-index

    4 publications

    520 citations

1–8 of 26

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 246 citations

    2

    h-index

  2. Applied and Environmental Microbiology

    AEM · 1 publications · 115 citations

    1

    h-index

  3. 1

    h-index

  4. Environmental Health Perspectives

    EHP · 1 publications · 22 citations

    1

    h-index

  5. Archives of Toxicology

    1 publications · 90 citations

    1

    h-index

1–5