Concepedia

Editing Window Optimization

Editing Window Optimization is a methodological strategy in base editing that refines the spatial range of target nucleotide modification by minimizing off-target edits and maximizing on-target efficiency within a defined genomic window.

18

Publications

673

Citations

167

Authors

54

Institutions

Publications per year

2017–2026

18

Parents

Publications

18

BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity

Wen G. Jiang, Songjie Feng, Shisheng Huang et al. · Cell Research · 2018 · 124 citations · Full text

, , +7

Expanding targeting scope, editing window, and base transition capability of base editing in <i>Corynebacterium glutamicum</i>

Yu Wang, Ye Liu, Junwei Li et al. · Biotechnology and Bioengineering · 2019 · 63 citations

, , +16

TRADES: Targeted RNA Demethylation by SunTag System

Jing Mo, Zonggui Chen, Shanshan Qin et al. · Advanced Science · 2020 · 60 citations · Full text

, , +11

Predicting base editing outcomes using position-specific sequence determinants

Ananth Pallaseni, Elin Madli Peets, Jonas Koeppel et al. · Nucleic Acids Research · 2022 · 46 citations · Full text

, , +13

Efficient base editing with high precision in rabbits using YFE-BE4max

Zhiquan Liu, Siyu Chen, Huanhuan Shan et al. · Cell Death and Disease · 2020 · 45 citations · Full text

, , +10

1–5 of 18

Authors

167

  1. XH
    Xingxu Huang

    ShanghaiTech University, China

    2 publications · 136 citations

    2

    h-index

  2. SH
    Shisheng Huang

    ShanghaiTech University, China

    2 publications · 136 citations

    2

    h-index

  3. SC
    Siyu Chen

    Jilin University, China

    2 publications · 84 citations

    2

    h-index

  4. HS
    Huanhuan Shan

    Jilin University, China

    2 publications · 84 citations

    2

    h-index

  5. LL
    Liangxue Lai

    Guangzhou Institutes of Biomedicine and Health, China

    2 publications · 84 citations

    2

    h-index

1–5 of 167

Institutions

54

  1. Chinese Academy of Sciences

    Beijing, China

    6 h-index

    29 publications

    1.3K citations

  2. University of Chinese Academy of Sciences

    Beijing, China

    3 h-index

    13 publications

    522 citations

  3. South China Normal University

    Guangzhou, China

    2 h-index

    4 publications

    93 citations

  4. ShanghaiTech University

    Shanghai, China

    2 h-index

    18 publications

    1.3K citations

  5. Jiangnan University

    Wuxi, China

    2 h-index

    15 publications

    481 citations

  6. Guangzhou Regenerative Medicine and Health Guangdong Laboratory

    Guangzhou, China

    2 h-index

    3 publications

    123 citations

  7. Center for Excellence in Brain Science and Intelligence Technology

    Shanghai, China

    2 h-index

    9 publications

    255 citations

  8. Jilin University

    Changchun, China

    2 h-index

    14 publications

    594 citations

1–8 of 54

Venues

  1. Advanced Science

    3 publications · 108 citations

    3

    h-index

  2. Nucleic Acids Research

    3 publications · 124 citations

    3

    h-index

  3. Nature Communications

    2 publications · 60 citations

    2

    h-index

  4. The FASEB Journal

    1 publications · 39 citations

    1

    h-index

  5. Molecular Therapy — Nucleic Acids

    1 publications · 12 citations

    1

    h-index

1–5