Concepedia

E7 Expression

E7 Expression is a molecular biomarker referring to the transcriptional or translational activity of the E7 oncogene of high-risk human papillomavirus, distinguishing it from other viral or cellular markers by its specific role in inactivating the retinoblastoma tumor suppressor protein to drive cervical epithelial dysplasia.

991

Publications

63.9K

Citations

4.6K

Authors

1.1K

Institutions

Publications per year

2017–2026

166

Parents

Publications

991

The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes

Karl Münger, William C. Phelps, Vivien J. Bubb et al. · Journal of Virology · 1989 · 1.3K citations · Full text

, , +15

Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.

Karl Münger, Bruce A. Werness, Nicholas J. Dyson et al. · The EMBO Journal · 1989 · 1.2K citations

, , +16

E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway.

S N Boyer, David E. Wazer, Vimla Band · PubMed · 1996 · 931 citations

, , +17

Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer-derived cell line and identification of the E7 protein.

David Smotkin, F O Wettstein · Proceedings of the National Academy of Sciences · 1986 · 666 citations

, , +17

The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A

William C. Phelps, Carole Yee, Karl Münger et al. · Cell · 1988 · 661 citations

, , +16

1–5 of 991

Authors

4.6K

  1. PF
    Paul F. Lambert

    University of Wisconsin–Madison, United States

    39 publications · 3.7K citations

    30

    h-index

  2. KM
    Karl Münger

    Harvard University, United States

    30 publications · 6.5K citations

    27

    h-index

  3. IH
    Ian H. Frazer

    The University of Queensland, Australia

    28 publications · 927 citations

    19

    h-index

  4. LG
    Lutz Gissmann

    German Cancer Research Center, Germany

    18 publications · 997 citations

    17

    h-index

  5. MT
    Massimo Tommasino

    Centre international de recherche sur le cancer, France

    17 publications · 1.1K citations

    17

    h-index

1–5 of 4.6K

Institutions

1.1K

  1. German Cancer Research Center

    Heidelberg, Germany

    34 h-index

    237 publications

    16.7K citations

  2. DKFZ-ZMBH Alliance

    Heidelberg, Germany

    31 h-index

    164 publications

    11.2K citations

  3. University of Wisconsin–Madison

    Madison, United States

    30 h-index

    103 publications

    11.2K citations

  4. National Cancer Institute

    Bethesda, United States

    28 h-index

    126 publications

    29.4K citations

  5. The University of Queensland

    Brisbane, Australia

    26 h-index

    161 publications

    6K citations

  6. Harvard University

    Cambridge, United States

    25 h-index

    88 publications

    10.5K citations

  7. Johns Hopkins University

    Baltimore, United States

    18 h-index

    92 publications

    6.7K citations

  8. National Institutes of Health

    Bethesda, United States

    17 h-index

    72 publications

    9K citations

1–8 of 1.1K

Venues

  1. Journal of Virology

    JVI · 113 publications · 13.4K citations

    62

    h-index

  2. PubMed

    Repository · 70 publications · 5.1K citations

    38

    h-index

  3. Virology

    61 publications · 2.8K citations

    32

    h-index

  4. Journal of General Virology

    41 publications · 1.6K citations

    25

    h-index

  5. Oncogene

    28 publications · 2.1K citations

    24

    h-index

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