Concepedia

Driver Mutation Timing

Driver Mutation Timing is a computational inference method that determines the temporal order of somatic driver mutations within the evolutionary history of a tumor’s subclonal architecture by integrating mutation accumulation patterns with phylogenetic reconstruction.

11

Publications

1.2K

Citations

112

Authors

40

Institutions

Publications per year

2017–2026

4

Parents

Publications

11

Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

Nicholas McGranahan, Francesco Favero, Elza C. de Bruin et al. · Science Translational Medicine · 2015 · 712 citations · Full text

, , +16

Early and multiple origins of metastatic lineages within primary tumors

Zi-Ming Zhao, Bixiao Zhao, Yalai Bai et al. · Proceedings of the National Academy of Sciences · 2016 · 167 citations · Full text

, , +17

Evolutionary histories of breast cancer and related clones

T Nishimura, Nobuyuki Kakiuchi, Kenichi Yoshida et al. · Nature · 2023 · 82 citations · Full text

, , +17

The genomic landscape of phaeochromocytoma

Aidan Flynn, Diana E. Benn, Roderick Clifton‐Bligh et al. · The Journal of Pathology · 2014 · 81 citations

, , +15

Phylogenetic reconstruction of myeloproliferative neoplasm reveals very early origins and lifelong evolution

Nicholas Williams, Joe Lee, Luiza Moore et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 54 citations · Full text

, , +17

1–5 of 11

Authors

112

  1. JP
    Jeffrey P. Townsend

    Yale University, United States

    2 publications · 198 citations

    2

    h-index

  2. AG
    A. Geoffrey Lyle

    University of California, Santa Cruz, United States

    1 publications · 13 citations

    1

    h-index

  3. ZS
    Zoltán Szállási

    Harvard University, United States

    1 publications · 712 citations

    1

    h-index

  4. EK
    Ellen Kephart

    University of California, Santa Cruz, United States

    1 publications · 13 citations

    1

    h-index

  5. SR
    Sofie R. Salama

    University of California, Santa Cruz, United States

    1 publications · 13 citations

    1

    h-index

1–5 of 112

Institutions

40

  1. Yale University

    New Haven, United States

    2 h-index

    10 publications

    1.5K citations

  2. Wellcome Sanger Institute

    Cambridge, United Kingdom

    1 h-index

    8 publications

    432 citations

  3. University College London

    London, United Kingdom

    1 h-index

    4 publications

    2.8K citations

  4. University of California, Santa Cruz

    Santa Cruz, United States

    1 h-index

    14 publications

    182 citations

  5. Kyoto University Hospital

    Kyoto, Japan

    1 h-index

    6 publications

    492 citations

  6. King Abdulaziz University

    Jeddah, Saudi Arabia

    1 h-index

    1 publications

    31 citations

  7. Peter MacCallum Cancer Centre

    Melbourne, Australia

    1 h-index

    10 publications

    810 citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    1 h-index

    2 publications

    26 citations

1–8 of 40

Venues

  1. The Journal of Pathology

    2 publications · 122 citations

    2

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 167 citations

    1

    h-index

  3. BMC Systems Biology

    1 publications · 26 citations

    1

    h-index

  4. BMC Bioinformatics

    1 publications · 19 citations

    1

    h-index

  5. Science Translational Medicine

    STM · 1 publications · 712 citations

    1

    h-index

1–5