Concepedia

Driver Mutation Identification

Driver Mutation Identification is a computational biology methodology that distinguishes somatic mutations conferring a selective growth advantage to cancer cells (driver mutations) from functionally neutral alterations (passenger mutations) by integrating genomic data with evolutionary and functional impact analyses.

313

Publications

39.7K

Citations

4.4K

Authors

1K

Institutions

Publications per year

2017–2026

185

Parents

Publications

313

Maftools: efficient and comprehensive analysis of somatic variants in cancer

Anand Mayakonda, De‐Chen Lin, Yassen Assenov et al. · Genome Research · 2018 · 5.4K citations · Full text

, , +17

A Landscape of Driver Mutations in Melanoma

Eran Hodis, Ian R. Watson, Gregory V. Kryukov et al. · Cell · 2012 · 2.6K citations · Full text

, , +12

Comprehensive Characterization of Cancer Driver Genes and Mutations

Matthew H. Bailey, Collin Tokheim, Eduard Porta‐Pardo et al. · Cell · 2018 · 2.5K citations · Full text

, , +17

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

Martin Peifer, Lynnette Fernandez‐Cuesta, Martin L. Sos et al. · Nature Genetics · 2012 · 1.4K citations · Full text

, , +16

The whole-genome landscape of medulloblastoma subtypes

Paul A. Northcott, Ivo Buchhalter, A. Sorana Morrissy et al. · Nature · 2017 · 1.2K citations · Full text

, , +17

1–5 of 313

Authors

4.4K

  1. GB
    Gordon B. Mills

    The University of Texas MD Anderson Cancer Center, United States

    7 publications · 1.5K citations

    7

    h-index

  2. GG
    Gad Getz

    Broad Institute, United States

    8 publications · 10.5K citations

    7

    h-index

  3. AG
    Abel González-Pérez

    Universitat Pompeu Fabra, Spain

    7 publications · 4.8K citations

    7

    h-index

  4. MS
    Michael S. Lawrence

    Broad Institute, United States

    11 publications · 10.6K citations

    7

    h-index

  5. NL
    Núria López-Bigas

    Universitat Pompeu Fabra, Spain

    7 publications · 4.8K citations

    7

    h-index

1–5 of 4.4K

Institutions

1K

  1. Harvard University

    Cambridge, United States

    21 h-index

    158 publications

    77.2K citations

  2. Dana-Farber Cancer Institute

    Boston, United States

    18 h-index

    155 publications

    72.8K citations

  3. The University of Texas MD Anderson Cancer Center

    Houston, United States

    14 h-index

    150 publications

    155.9K citations

  4. Broad Institute

    Cambridge, United States

    14 h-index

    268 publications

    262.8K citations

  5. Massachusetts General Hospital

    Boston, United States

    14 h-index

    111 publications

    79K citations

  6. Memorial Sloan Kettering Cancer Center

    New York, United States

    12 h-index

    105 publications

    31.2K citations

  7. Chinese Academy of Sciences

    Beijing, China

    12 h-index

    28 publications

    2.8K citations

  8. Universitat Pompeu Fabra

    Barcelona, Spain

    12 h-index

    83 publications

    27.3K citations

1–8 of 1K

Venues

  1. Bioinformatics

    15 publications · 1.8K citations

    14

    h-index

  2. Scientific Reports

    16 publications · 1.1K citations

    14

    h-index

  3. Nucleic Acids Research

    13 publications · 1.2K citations

    13

    h-index

  4. Oncotarget

    12 publications · 396 citations

    12

    h-index

  5. BMC Bioinformatics

    12 publications · 446 citations

    11

    h-index

1–5