Concepedia

Driver Mutation Discovery

Driver Mutation Discovery is a computational and statistical methodology in cancer genomics that identifies somatic mutations conferring a selective growth advantage to cancer cells by distinguishing them from functionally neutral passenger mutations.

420

Publications

52K

Citations

4.9K

Authors

1.2K

Institutions

Publications per year

2017–2026

219

Parents

Publications

420

Maftools: efficient and comprehensive analysis of somatic variants in cancer

Anand Mayakonda, De‐Chen Lin, Yassen Assenov et al. · Genome Research · 2018 · 5.4K citations · Full text

, , +17

Mutational landscape and significance across 12 major cancer types

Cyriac Kandoth, Michael D. McLellan, Fabio Vandin et al. · Nature · 2013 · 4.5K citations · Full text

, , +17

Comprehensive Characterization of Cancer Driver Genes and Mutations

Matthew H. Bailey, Collin Tokheim, Eduard Porta‐Pardo et al. · Cell · 2018 · 2.5K citations · Full text

, , +17

Universal Patterns of Selection in Cancer and Somatic Tissues

Iñigo Martincorena, Keiran Raine, Moritz Gerstung et al. · Cell · 2017 · 1.7K citations · Full text

, , +15

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

Martin Peifer, Lynnette Fernandez‐Cuesta, Martin L. Sos et al. · Nature Genetics · 2012 · 1.4K citations · Full text

, , +16

1–5 of 420

Authors

4.9K

  1. NL
    Núria López-Bigas

    Universitat Pompeu Fabra, Spain

    14 publications · 6K citations

    13

    h-index

  2. AG
    Abel González-Pérez

    Universitat Pompeu Fabra, Spain

    15 publications · 6.3K citations

    13

    h-index

  3. GG
    Gad Getz

    Broad Institute, United States

    14 publications · 9.7K citations

    11

    h-index

  4. MS
    Michael S. Lawrence

    Broad Institute, United States

    14 publications · 9.3K citations

    10

    h-index

  5. DT
    David Tamborero

    Universitat de Barcelona, Spain

    10 publications · 5.4K citations

    10

    h-index

1–5 of 4.9K

Institutions

1.2K

  1. Harvard University

    Cambridge, United States

    28 h-index

    199 publications

    69.3K citations

  2. Universitat Pompeu Fabra

    Barcelona, Spain

    22 h-index

    172 publications

    42.4K citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    21 h-index

    170 publications

    65.9K citations

  4. Broad Institute

    Cambridge, United States

    21 h-index

    358 publications

    230.3K citations

  5. Massachusetts General Hospital

    Boston, United States

    18 h-index

    144 publications

    84.1K citations

  6. Institució Catalana de Recerca i Estudis Avançats

    Barcelona, Spain

    17 h-index

    34 publications

    14.8K citations

  7. Chinese Academy of Sciences

    Beijing, China

    17 h-index

    84 publications

    9.3K citations

  8. Memorial Sloan Kettering Cancer Center

    New York, United States

    16 h-index

    185 publications

    47K citations

1–8 of 1.2K

Venues

  1. Bioinformatics

    22 publications · 1.9K citations

    18

    h-index

  2. Nature Communications

    19 publications · 1.6K citations

    17

    h-index

  3. Nucleic Acids Research

    17 publications · 1.5K citations

    16

    h-index

  4. Scientific Reports

    18 publications · 1.4K citations

    15

    h-index

  5. BMC Bioinformatics

    19 publications · 699 citations

    14

    h-index

1–5