Concepedia

Downstream Process Scale-up

Downstream Process Scale-Up is the systematic enlargement of purification and recovery operations from laboratory to industrial scale within a bioprocess, distinguished by the adaptation of separation, concentration, and polishing steps to maintain product quality, yield, and efficiency under large-scale constraints.

16

Publications

762

Citations

111

Authors

31

Institutions

Publications per year

2017–2026

8

Parents

Publications

16

Downstream bioprocessing: recent advances and future promise

Steven M. Cramer, Melissa Holstein · Current Opinion in Chemical Engineering · 2011 · 136 citations

, , +16

Scaled‐up manufacturing of recombinant antibodies produced by plant cells in a 200‐L orbitally‐shaken disposable bioreactor

Nicole Raven, Stefan Rasche, Christoph Kuehn et al. · Biotechnology and Bioengineering · 2014 · 114 citations

, , +15

Scaling-up of a B-phycoerythrin production and purification bioprocess involving aqueous two-phase systems: Practical experiences

Federico Ruiz‐Ruiz, Jorge Benavides, Marco Rito‐Palomares · Process Biochemistry · 2013 · 75 citations

, , +17

Development of Large-Scale Downstream Processing for Lentiviral Vectors

Anniina J. Valkama, Igor Oruetxebarria, Eevi M. Lipponen et al. · Molecular Therapy — Methods & Clinical Development · 2020 · 68 citations · Full text

, , +17

Process scale-up of an efficient acid-catalyzed steam pretreatment of rice straw for xylitol production by C. Tropicalis MTCC 6192

S. P. Singh, Dalveer Kaur, Sudesh Kumar Yadav et al. · Bioresource Technology · 2020 · 57 citations

, , +10

1–5 of 16

Authors

111

  1. GJ
    Guido Jach

    Max Planck Institute for Plant Breeding Research, Germany

    1 publications · 17 citations

    1

    h-index

  2. KK
    Kashyap Kumar Dubey

    Maharshi Dayanand University, India

    1 publications · 44 citations

    1

    h-index

  3. NP
    Nigel Parker

    University of Eastern Finland, Finland

    1 publications · 68 citations

    1

    h-index

  4. SG
    Sarah Gretzinger

    Karlsruhe Institute of Technology, Germany

    1 publications · 26 citations

    1

    h-index

  5. MK
    Marcin Konkol

    New Chemical Syntheses Institute, Poland

    1 publications · 31 citations

    1

    h-index

1–5 of 111

Institutions

31

  1. Justus-Liebig-Universität Gießen

    Giessen, Germany

    2 h-index

    3 publications

    176 citations

  2. Fraunhofer Institute for Molecular Biology and Applied Ecology

    Schmallenberg, Germany

    2 h-index

    6 publications

    601 citations

  3. RWTH Aachen University

    Aachen, Germany

    2 h-index

    7 publications

    414 citations

  4. University of Eastern Finland

    Joensuu, Finland

    1 h-index

    6 publications

    408 citations

  5. Karlsruhe Institute of Technology

    Karlsruhe, Germany

    1 h-index

    8 publications

    208 citations

  6. Merck KGaA, Darmstadt (Germany)

    Darmstadt, Germany

    1 h-index

    1 publications

    34 citations

  7. University of Tübingen

    Tübingen, Germany

    1 h-index

    3 publications

    93 citations

  8. Agency for Science, Technology and Research

    Singapore, Singapore

    1 h-index

    6 publications

    318 citations

1–8 of 31

Venues

  1. Process Biochemistry

    2 publications · 119 citations

    2

    h-index

  2. Protein Expression and Purification

    1 publications · 53 citations

    1

    h-index

  3. Current Opinion in Chemical Engineering

    1 publications · 136 citations

    1

    h-index

  4. 1

    h-index

  5. Vaccine

    1 publications · 11 citations

    1

    h-index

1–5